The biological functions of europium-containing biomaterials: A systematic review
The biological functions of rare-earth elements (REEs) have become a focus of intense research. Recent studies have demonstrated that ion doping or alloying of some REEs can optimize the properties of traditional biomaterials. Europium (Eu), which is an REE with low toxicity and good biocompatibilit...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-04-01
|
| Series: | Materials Today Bio |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006423000558 |
| _version_ | 1797854314942693376 |
|---|---|
| author | Likun Wu Fan Yang Yijia Xue Ranli Gu Hao Liu Dandan Xia Yunsong Liu |
| author_facet | Likun Wu Fan Yang Yijia Xue Ranli Gu Hao Liu Dandan Xia Yunsong Liu |
| author_sort | Likun Wu |
| collection | DOAJ |
| description | The biological functions of rare-earth elements (REEs) have become a focus of intense research. Recent studies have demonstrated that ion doping or alloying of some REEs can optimize the properties of traditional biomaterials. Europium (Eu), which is an REE with low toxicity and good biocompatibility, has promising applications in biomedicine. This article systematically reviews the osteogenic, angiogenic, neuritogenic, antibacterial, and anti-tumor properties of Eu-containing biomaterials, thereby paving the way for biomedical applications of Eu. Data collection for this review was completed in October 2022, and 30 relevant articles were finally included. Most articles indicated that doping of Eu ions or Eu-compound nanoparticles in biomaterials can improve their osteogenic, angiogenic, neuritogenic, antibacterial, and anti-tumor properties. The angiogenic, antibacterial, and potential neuritogenic effects of Eu(OH)3 nanoparticles have also been demonstrated. |
| first_indexed | 2024-04-09T20:03:58Z |
| format | Article |
| id | doaj.art-1fecc7153db84cdba3e68745fbcb2b56 |
| institution | Directory Open Access Journal |
| issn | 2590-0064 |
| language | English |
| last_indexed | 2024-04-09T20:03:58Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj.art-1fecc7153db84cdba3e68745fbcb2b562023-04-02T06:14:56ZengElsevierMaterials Today Bio2590-00642023-04-0119100595The biological functions of europium-containing biomaterials: A systematic reviewLikun Wu0Fan Yang1Yijia Xue2Ranli Gu3Hao Liu4Dandan Xia5Yunsong Liu6Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, ChinaDepartment of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, ChinaNational Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, China; Department of Dental Materials, Peking University School and Hospital of Stomatology, Beijing, 100081, China; Corresponding author. Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, China.Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health, NMPA Key Laboratory for Dental Materials, Beijing, 100081, China; Corresponding author. Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, China.The biological functions of rare-earth elements (REEs) have become a focus of intense research. Recent studies have demonstrated that ion doping or alloying of some REEs can optimize the properties of traditional biomaterials. Europium (Eu), which is an REE with low toxicity and good biocompatibility, has promising applications in biomedicine. This article systematically reviews the osteogenic, angiogenic, neuritogenic, antibacterial, and anti-tumor properties of Eu-containing biomaterials, thereby paving the way for biomedical applications of Eu. Data collection for this review was completed in October 2022, and 30 relevant articles were finally included. Most articles indicated that doping of Eu ions or Eu-compound nanoparticles in biomaterials can improve their osteogenic, angiogenic, neuritogenic, antibacterial, and anti-tumor properties. The angiogenic, antibacterial, and potential neuritogenic effects of Eu(OH)3 nanoparticles have also been demonstrated.http://www.sciencedirect.com/science/article/pii/S2590006423000558AngiogenesisAntibacterialAnti-tumorEuropiumNerve regenerationOsteogenesis |
| spellingShingle | Likun Wu Fan Yang Yijia Xue Ranli Gu Hao Liu Dandan Xia Yunsong Liu The biological functions of europium-containing biomaterials: A systematic review Materials Today Bio Angiogenesis Antibacterial Anti-tumor Europium Nerve regeneration Osteogenesis |
| title | The biological functions of europium-containing biomaterials: A systematic review |
| title_full | The biological functions of europium-containing biomaterials: A systematic review |
| title_fullStr | The biological functions of europium-containing biomaterials: A systematic review |
| title_full_unstemmed | The biological functions of europium-containing biomaterials: A systematic review |
| title_short | The biological functions of europium-containing biomaterials: A systematic review |
| title_sort | biological functions of europium containing biomaterials a systematic review |
| topic | Angiogenesis Antibacterial Anti-tumor Europium Nerve regeneration Osteogenesis |
| url | http://www.sciencedirect.com/science/article/pii/S2590006423000558 |
| work_keys_str_mv | AT likunwu thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT fanyang thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT yijiaxue thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT ranligu thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT haoliu thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT dandanxia thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT yunsongliu thebiologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT likunwu biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT fanyang biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT yijiaxue biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT ranligu biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT haoliu biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT dandanxia biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview AT yunsongliu biologicalfunctionsofeuropiumcontainingbiomaterialsasystematicreview |