Planning in silico screening and experimental study of the hypoglycemic derivatives of cyclic guanidines

Planning in silico screening and experimental study of the hypoglycemic derivatives of cyclic guanidines

This article is devoted to the search for new cyclic guanidine derivatives with hypoglycemic activity by means of in silico methods. The results of computer prediction of hypoglycemic effect for nine classes of these compounds were analyzed. Two perspective classes of cyclic guanidine derivatives ha...

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Bibliographic Details
Main Authors: P. M. Vasiliev, A. A. Spasov, K. V. Lenskaya, V. V. Poroikov, D. A. Filimonov, V. A. Anisimova
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2014-12-01
Series:Кубанский научный медицинский вестник
Subjects:
циклические гуанидины
гипогликемическая активность
методы in silico
диабет
компьютерное планирование экспериментов
cyclic guanidines
hypoglycemic activity
in silico methods
diabetes
computer planning of experiments
Online Access:https://ksma.elpub.ru/jour/article/view/229

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