Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
BackgroundTo determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. Materials and MethodsIn this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed....
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2011-01-01
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| Series: | International Journal of Fertility and Sterility |
| Subjects: | |
| Online Access: | http://www.ijfs.ir/article_45072_5664deb43222d8445811c84482161498.pdf |
| _version_ | 1818452677057576960 |
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| author | Saghar Salehpour Ozra Manzor-al-ajdad Elham Neisani Samani Alireza Abadi |
| author_facet | Saghar Salehpour Ozra Manzor-al-ajdad Elham Neisani Samani Alireza Abadi |
| author_sort | Saghar Salehpour |
| collection | DOAJ |
| description | BackgroundTo determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. Materials and MethodsIn this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. ResultsThe mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. Conclusion These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship. |
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| format | Article |
| id | doaj.art-1ffb685146444c8583366c69690ed8a2 |
| institution | Directory Open Access Journal |
| issn | 2008-076X 2008-0778 |
| language | English |
| last_indexed | 2024-12-14T21:26:53Z |
| publishDate | 2011-01-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | International Journal of Fertility and Sterility |
| spelling | doaj.art-1ffb685146444c8583366c69690ed8a22022-12-21T22:46:46ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782011-01-014416817145072Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian SyndromeSaghar SalehpourOzra Manzor-al-ajdadElham Neisani SamaniAlireza AbadiBackgroundTo determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. Materials and MethodsIn this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. ResultsThe mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. Conclusion These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.http://www.ijfs.ir/article_45072_5664deb43222d8445811c84482161498.pdfpolycystic ovary syndromehomocysteine bloodcardiovascular disease |
| spellingShingle | Saghar Salehpour Ozra Manzor-al-ajdad Elham Neisani Samani Alireza Abadi Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome International Journal of Fertility and Sterility polycystic ovary syndrome homocysteine blood cardiovascular disease |
| title | Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome |
| title_full | Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome |
| title_fullStr | Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome |
| title_full_unstemmed | Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome |
| title_short | Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome |
| title_sort | evaluation of homocysteine levels in patients with polycystic ovarian syndrome |
| topic | polycystic ovary syndrome homocysteine blood cardiovascular disease |
| url | http://www.ijfs.ir/article_45072_5664deb43222d8445811c84482161498.pdf |
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