Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients
Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2006-05-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000300019 |
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| author | SAG Macoris MF Sugizaki MTS Peraçoli SMG Bosco F Hebeler-Barbosa LB Simões RC Theodoro LA Trinca E Bagagli |
| author_facet | SAG Macoris MF Sugizaki MTS Peraçoli SMG Bosco F Hebeler-Barbosa LB Simões RC Theodoro LA Trinca E Bagagli |
| author_sort | SAG Macoris |
| collection | DOAJ |
| description | Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features. |
| first_indexed | 2024-03-12T08:12:33Z |
| format | Article |
| id | doaj.art-1ffcd3f4028543a9ba0a2dea0b21e3a1 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T08:12:33Z |
| publishDate | 2006-05-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-1ffcd3f4028543a9ba0a2dea0b21e3a12023-09-02T19:06:32ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602006-05-01101333133410.1590/S0074-02762006000300019Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patientsSAG MacorisMF SugizakiMTS PeraçoliSMG BoscoF Hebeler-BarbosaLB SimõesRC TheodoroLA TrincaE BagagliParacoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000300019Paracoccidioides brasiliensisvirulencehamsterDasypus novemcinctus |
| spellingShingle | SAG Macoris MF Sugizaki MTS Peraçoli SMG Bosco F Hebeler-Barbosa LB Simões RC Theodoro LA Trinca E Bagagli Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients Memorias do Instituto Oswaldo Cruz Paracoccidioides brasiliensis virulence hamster Dasypus novemcinctus |
| title | Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
| title_full | Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
| title_fullStr | Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
| title_full_unstemmed | Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
| title_short | Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
| title_sort | virulence attenuation and phenotypic variation of paracoccidioides brasiliensis isolates obtained from armadillos and patients |
| topic | Paracoccidioides brasiliensis virulence hamster Dasypus novemcinctus |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000300019 |
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