ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses
Objective To evaluate the feasibility and diagnostic performance of acoustic radiation force impulse (ARFI) elastography in different omental masses (OM).Design This was a retrospective analysis of 106 patients with OM defined as omental thickness ≥1 cm, who underwent abdominal B-mode ultrasound (US...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-07-01
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| Series: | BMJ Open Gastroenterology |
| Online Access: | https://bmjopengastro.bmj.com/content/9/1/e000901.full |
| _version_ | 1797782534225920000 |
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| author | Amjad Alhyari Christian Görg Christoph Frank Dietrich Corrina Trenker Lena Strauch Ehsan Safai Zadeh |
| author_facet | Amjad Alhyari Christian Görg Christoph Frank Dietrich Corrina Trenker Lena Strauch Ehsan Safai Zadeh |
| author_sort | Amjad Alhyari |
| collection | DOAJ |
| description | Objective To evaluate the feasibility and diagnostic performance of acoustic radiation force impulse (ARFI) elastography in different omental masses (OM).Design This was a retrospective analysis of 106 patients with OM defined as omental thickness ≥1 cm, who underwent abdominal B-mode ultrasound (US) and standardised ARFI examinations of the OM between September 2018 and June 2021 at our university hospital. A cytohistological confirmation was available in 91/106 (85.8%) of all OM, including all 65/65 (100%) malignant OM (mOM) and 26/41 (63.4%) of benign OM (bOM). In 15/41 (36.6%) of bOM; cross-sectional imaging and or US follow-up with a mean duration of 19.8±3.1 months was performed. To examine the mean ARFI velocities (MAV) for potential cut-off values between bOM and mOM a receiver operating characteristic analysis was implemented.Results The MAV in the mOM group (2.71±1.04 m/s) was significantly higher than that of bOM group (1.27±0.87 m/s) (p<0.001). Using 1.97 m/s as a cut-off yielded a sensitivity and specificity of 76.9% and 85.4%, respectively, in diagnosing mOM (area under the curve=0.851, 95% CI=0.774 to 0.928).Conclusion ARFI elastography is feasible in the omentum and may represent a good non-invasive additional tool in differentiating bOM from mOM. |
| first_indexed | 2024-03-13T00:12:17Z |
| format | Article |
| id | doaj.art-1ffd558e0f904ff58ea1e6674ca1c6a1 |
| institution | Directory Open Access Journal |
| issn | 2054-4774 |
| language | English |
| last_indexed | 2024-03-13T00:12:17Z |
| publishDate | 2022-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Gastroenterology |
| spelling | doaj.art-1ffd558e0f904ff58ea1e6674ca1c6a12023-07-12T09:00:07ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742022-07-019110.1136/bmjgast-2022-000901ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental massesAmjad Alhyari0Christian Görg1Christoph Frank Dietrich2Corrina Trenker3Lena Strauch4Ehsan Safai Zadeh5Interdisciplinary Centre of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Philipp University of Marburg, Baldingerstraße Marburg, Marburg, GermanyInterdisciplinary Centre of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Philipp University of Marburg, Baldingerstraße Marburg, Marburg, GermanyDepartment of Internal Medicine, Kliniken Hirslanden Bern, Salem und Permanence, Bern, SwitzerlandInterdisciplinary Centre of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Philipp University of Marburg, Baldingerstraße Marburg, Marburg, GermanyInterdisciplinary Centre of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Philipp University of Marburg, Baldingerstraße Marburg, Marburg, GermanyInterdisciplinary Centre of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Philipp University of Marburg, Baldingerstraße Marburg, Marburg, GermanyObjective To evaluate the feasibility and diagnostic performance of acoustic radiation force impulse (ARFI) elastography in different omental masses (OM).Design This was a retrospective analysis of 106 patients with OM defined as omental thickness ≥1 cm, who underwent abdominal B-mode ultrasound (US) and standardised ARFI examinations of the OM between September 2018 and June 2021 at our university hospital. A cytohistological confirmation was available in 91/106 (85.8%) of all OM, including all 65/65 (100%) malignant OM (mOM) and 26/41 (63.4%) of benign OM (bOM). In 15/41 (36.6%) of bOM; cross-sectional imaging and or US follow-up with a mean duration of 19.8±3.1 months was performed. To examine the mean ARFI velocities (MAV) for potential cut-off values between bOM and mOM a receiver operating characteristic analysis was implemented.Results The MAV in the mOM group (2.71±1.04 m/s) was significantly higher than that of bOM group (1.27±0.87 m/s) (p<0.001). Using 1.97 m/s as a cut-off yielded a sensitivity and specificity of 76.9% and 85.4%, respectively, in diagnosing mOM (area under the curve=0.851, 95% CI=0.774 to 0.928).Conclusion ARFI elastography is feasible in the omentum and may represent a good non-invasive additional tool in differentiating bOM from mOM.https://bmjopengastro.bmj.com/content/9/1/e000901.full |
| spellingShingle | Amjad Alhyari Christian Görg Christoph Frank Dietrich Corrina Trenker Lena Strauch Ehsan Safai Zadeh ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses BMJ Open Gastroenterology |
| title | ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses |
| title_full | ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses |
| title_fullStr | ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses |
| title_full_unstemmed | ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses |
| title_short | ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses |
| title_sort | arfi elastography of the omentum feasibility and diagnostic performance in differentiating benign from malignant omental masses |
| url | https://bmjopengastro.bmj.com/content/9/1/e000901.full |
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