Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED
Summary: Quaternary ammonium compounds exhibit diverse applications as antibiotics, as surfactants, in paper industries, in sewage treatment, and in aquaculture. Here, we present a protocol for synthesizing a library of bioactive quaternary ammonium betaine derivatives under blue LED in water. We de...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | STAR Protocols |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166724000558 |
| _version_ | 1797317104548970496 |
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| author | Suchismita Rath Subhabrata Sen |
| author_facet | Suchismita Rath Subhabrata Sen |
| author_sort | Suchismita Rath |
| collection | DOAJ |
| description | Summary: Quaternary ammonium compounds exhibit diverse applications as antibiotics, as surfactants, in paper industries, in sewage treatment, and in aquaculture. Here, we present a protocol for synthesizing a library of bioactive quaternary ammonium betaine derivatives under blue LED in water. We describe steps for preparing diazo compounds, synthesizing glycine betaine derivatives, and isolating pure final compounds via precipitation from an aqueous reaction mixture. This protocol promotes a sustainable approach by using water as the reaction medium and room temperature reactions.For complete details on the use and execution of this protocol, please refer to Rath et al. (2023).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics. |
| first_indexed | 2024-03-08T03:29:04Z |
| format | Article |
| id | doaj.art-1fff34abb76f4a23b52f2c278b9a5a05 |
| institution | Directory Open Access Journal |
| issn | 2666-1667 |
| language | English |
| last_indexed | 2024-03-08T03:29:04Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | STAR Protocols |
| spelling | doaj.art-1fff34abb76f4a23b52f2c278b9a5a052024-02-11T05:12:09ZengElsevierSTAR Protocols2666-16672024-03-0151102890Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LEDSuchismita Rath0Subhabrata Sen1Department of Chemistry, School of Natural Sciences, Shiv Nadar Institution of Eminence Deemed to be University, Gautam Buddha Nagar, Chithera, Dadri, UP 201310, IndiaDepartment of Chemistry, School of Natural Sciences, Shiv Nadar Institution of Eminence Deemed to be University, Gautam Buddha Nagar, Chithera, Dadri, UP 201310, India; Corresponding authorSummary: Quaternary ammonium compounds exhibit diverse applications as antibiotics, as surfactants, in paper industries, in sewage treatment, and in aquaculture. Here, we present a protocol for synthesizing a library of bioactive quaternary ammonium betaine derivatives under blue LED in water. We describe steps for preparing diazo compounds, synthesizing glycine betaine derivatives, and isolating pure final compounds via precipitation from an aqueous reaction mixture. This protocol promotes a sustainable approach by using water as the reaction medium and room temperature reactions.For complete details on the use and execution of this protocol, please refer to Rath et al. (2023).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.http://www.sciencedirect.com/science/article/pii/S2666166724000558Health SciencesChemistryMaterial sciences |
| spellingShingle | Suchismita Rath Subhabrata Sen Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED STAR Protocols Health Sciences Chemistry Material sciences |
| title | Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED |
| title_full | Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED |
| title_fullStr | Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED |
| title_full_unstemmed | Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED |
| title_short | Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED |
| title_sort | protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue led |
| topic | Health Sciences Chemistry Material sciences |
| url | http://www.sciencedirect.com/science/article/pii/S2666166724000558 |
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