Dexmedetomidine Protects Cerebellar Neurons against Hyperoxia-Induced Oxidative Stress and Apoptosis in the Juvenile Rat

Dexmedetomidine Protects Cerebellar Neurons against Hyperoxia-Induced Oxidative Stress and Apoptosis in the Juvenile Rat

The risk of oxidative stress is unavoidable in preterm infants and increases the risk of neonatal morbidities. Premature infants often require sedation and analgesia, and the commonly used opioids and benzodiazepines are associated with adverse effects. Impairment of cerebellar functions during cogn...

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Bibliographic Details
Main Authors: Robert Puls, Clarissa von Haefen, Christoph Bührer, Stefanie Endesfelder
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
hyperoxia
oxidative stress
cerebellum
dexmedetomidine
postnatal developing brain
newborn rat
Online Access:https://www.mdpi.com/1422-0067/24/9/7804

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