Malassezia spp. Yeasts of Emerging Concern in Fungemia
Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-07-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fcimb.2020.00370/full |
| _version_ | 1818455300919787520 |
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| author | Wafa Rhimi Bart Theelen Teun Boekhout Teun Boekhout Teun Boekhout Domenico Otranto Domenico Otranto Claudia Cafarchia |
| author_facet | Wafa Rhimi Bart Theelen Teun Boekhout Teun Boekhout Teun Boekhout Domenico Otranto Domenico Otranto Claudia Cafarchia |
| author_sort | Wafa Rhimi |
| collection | DOAJ |
| description | Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches. |
| first_indexed | 2024-12-14T22:08:36Z |
| format | Article |
| id | doaj.art-2006395c55f343e9947a01e7dbcd6a3c |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-12-14T22:08:36Z |
| publishDate | 2020-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-2006395c55f343e9947a01e7dbcd6a3c2022-12-21T22:45:48ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882020-07-011010.3389/fcimb.2020.00370540312Malassezia spp. Yeasts of Emerging Concern in FungemiaWafa Rhimi0Bart Theelen1Teun Boekhout2Teun Boekhout3Teun Boekhout4Domenico Otranto5Domenico Otranto6Claudia Cafarchia7Dipartimento di Medicina Veterinaria, Università degli Studi “Aldo Moro”, Bari, ItalyYeast Research, Westerdijk Fungal Biodiversity Institute, Utrecht, NetherlandsYeast Research, Westerdijk Fungal Biodiversity Institute, Utrecht, NetherlandsThe Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, Amsterdam, NetherlandsShanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Military Medical University, Shanghai, ChinaDipartimento di Medicina Veterinaria, Università degli Studi “Aldo Moro”, Bari, ItalyFaculty of Veterinary Sciences, Bu-Ali Sina University, Hamedan, IranDipartimento di Medicina Veterinaria, Università degli Studi “Aldo Moro”, Bari, ItalyMalassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.https://www.frontiersin.org/article/10.3389/fcimb.2020.00370/fullMalassezia spp.epidemiologypathogenesisfungemiadiagnosistherapy |
| spellingShingle | Wafa Rhimi Bart Theelen Teun Boekhout Teun Boekhout Teun Boekhout Domenico Otranto Domenico Otranto Claudia Cafarchia Malassezia spp. Yeasts of Emerging Concern in Fungemia Frontiers in Cellular and Infection Microbiology Malassezia spp. epidemiology pathogenesis fungemia diagnosis therapy |
| title | Malassezia spp. Yeasts of Emerging Concern in Fungemia |
| title_full | Malassezia spp. Yeasts of Emerging Concern in Fungemia |
| title_fullStr | Malassezia spp. Yeasts of Emerging Concern in Fungemia |
| title_full_unstemmed | Malassezia spp. Yeasts of Emerging Concern in Fungemia |
| title_short | Malassezia spp. Yeasts of Emerging Concern in Fungemia |
| title_sort | malassezia spp yeasts of emerging concern in fungemia |
| topic | Malassezia spp. epidemiology pathogenesis fungemia diagnosis therapy |
| url | https://www.frontiersin.org/article/10.3389/fcimb.2020.00370/full |
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