Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina
<i>Background and Objectives:</i> The COVID-19 pandemic has led to significant changes globally, which has also affected patients with type 1 diabetes mellitus (T1DM). This study aimed to determine the incidence of T1DM and the characteristics of diabetic ketoacidosis (DKA) during the pa...
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MDPI AG
2022-07-01
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| 丛编: | Medicina |
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| 在线阅读: | https://www.mdpi.com/1648-9144/58/8/1013 |
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| author | Ivana Vorgučin Marijana Savin Đurđina Stanković Dejan Miljković Tatjana Ilić Danijela Simić Mirjana Vrebalov Borko Milanović Nenad Barišić Vesna Stojanović Gordana Vijatov-Đurić Katarina Koprivšek Gordana Vilotijević-Dautović Jelena Antić |
| author_facet | Ivana Vorgučin Marijana Savin Đurđina Stanković Dejan Miljković Tatjana Ilić Danijela Simić Mirjana Vrebalov Borko Milanović Nenad Barišić Vesna Stojanović Gordana Vijatov-Đurić Katarina Koprivšek Gordana Vilotijević-Dautović Jelena Antić |
| author_sort | Ivana Vorgučin |
| collection | DOAJ |
| description | <i>Background and Objectives:</i> The COVID-19 pandemic has led to significant changes globally, which has also affected patients with type 1 diabetes mellitus (T1DM). This study aimed to determine the incidence of T1DM and the characteristics of diabetic ketoacidosis (DKA) during the pandemic comparing it to pre-pandemic period. <i>Materials and Methods:</i> Data from patients <19 years with newly diagnosed T1DM between 1st January 2017 and 31st December 2021 from four regional centers in Vojvodina were retrospectively collected and analyzed. <i>Results:</i> In 2021, the highest incidence of T1DM in the last five years was recorded, 17.3/100,000. During the pandemic period (2020–2021), there were 99 new-onset T1DM, of which 42.4% presented in DKA, which is significantly higher than in the pre-pandemic period (34.1%). During the pandemic, symptom duration of T1DM lasted significantly longer than before the COVID-19 period. At the age of 10–14 years, the highest incidence of T1DM and COVID-19, the highest frequency rate of DKA, and severe DKA were observed. <i>Conclusions:</i> The pandemic is associated with a high incidence rate of T1DM, longer duration of symptoms of T1DM, a high frequency of DKA, and a severe DKA at diagnosis. Patients aged 10–14 years are a risk group for the occurrence of T1DM with severe clinical presentation. Additional studies are needed with a longer study period and in a wider geographical area, with data on exposure to COVID-19 infection, the permanence of new-onset T1DM, and the psychosocial impact of the pandemic. |
| first_indexed | 2024-03-09T04:07:28Z |
| format | Article |
| id | doaj.art-20068f87194a44c5864521bcf93609ee |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T04:07:28Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-20068f87194a44c5864521bcf93609ee2023-12-03T14:04:28ZengMDPI AGMedicina1010-660X1648-91442022-07-01588101310.3390/medicina58081013Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in VojvodinaIvana Vorgučin0Marijana Savin1Đurđina Stanković2Dejan Miljković3Tatjana Ilić4Danijela Simić5Mirjana Vrebalov6Borko Milanović7Nenad Barišić8Vesna Stojanović9Gordana Vijatov-Đurić10Katarina Koprivšek11Gordana Vilotijević-Dautović12Jelena Antić13Institute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, SerbiaGeneral Hospital Subotica, 24000 Subotica, SerbiaGeneral Hospital Sombor, 25000 Sombor, SerbiaGeneral Hospital Zrenjanin, 23000 Zrenjanin, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, SerbiaInstitute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, Serbia<i>Background and Objectives:</i> The COVID-19 pandemic has led to significant changes globally, which has also affected patients with type 1 diabetes mellitus (T1DM). This study aimed to determine the incidence of T1DM and the characteristics of diabetic ketoacidosis (DKA) during the pandemic comparing it to pre-pandemic period. <i>Materials and Methods:</i> Data from patients <19 years with newly diagnosed T1DM between 1st January 2017 and 31st December 2021 from four regional centers in Vojvodina were retrospectively collected and analyzed. <i>Results:</i> In 2021, the highest incidence of T1DM in the last five years was recorded, 17.3/100,000. During the pandemic period (2020–2021), there were 99 new-onset T1DM, of which 42.4% presented in DKA, which is significantly higher than in the pre-pandemic period (34.1%). During the pandemic, symptom duration of T1DM lasted significantly longer than before the COVID-19 period. At the age of 10–14 years, the highest incidence of T1DM and COVID-19, the highest frequency rate of DKA, and severe DKA were observed. <i>Conclusions:</i> The pandemic is associated with a high incidence rate of T1DM, longer duration of symptoms of T1DM, a high frequency of DKA, and a severe DKA at diagnosis. Patients aged 10–14 years are a risk group for the occurrence of T1DM with severe clinical presentation. Additional studies are needed with a longer study period and in a wider geographical area, with data on exposure to COVID-19 infection, the permanence of new-onset T1DM, and the psychosocial impact of the pandemic.https://www.mdpi.com/1648-9144/58/8/1013COVID-19pandemictype 1 diabetes mellitusdiabetic ketoacidosisincidencechildren |
| spellingShingle | Ivana Vorgučin Marijana Savin Đurđina Stanković Dejan Miljković Tatjana Ilić Danijela Simić Mirjana Vrebalov Borko Milanović Nenad Barišić Vesna Stojanović Gordana Vijatov-Đurić Katarina Koprivšek Gordana Vilotijević-Dautović Jelena Antić Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina Medicina COVID-19 pandemic type 1 diabetes mellitus diabetic ketoacidosis incidence children |
| title | Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina |
| title_full | Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina |
| title_fullStr | Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina |
| title_full_unstemmed | Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina |
| title_short | Incidence of Type 1 Diabetes Mellitus and Characteristics of Diabetic Ketoacidosis in Children and Adolescents during the First Two Years of the COVID-19 Pandemic in Vojvodina |
| title_sort | incidence of type 1 diabetes mellitus and characteristics of diabetic ketoacidosis in children and adolescents during the first two years of the covid 19 pandemic in vojvodina |
| topic | COVID-19 pandemic type 1 diabetes mellitus diabetic ketoacidosis incidence children |
| url | https://www.mdpi.com/1648-9144/58/8/1013 |
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