Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

Terminal bd oxidases endow bacterial pathogens with resistance to cellular stressors. The authors report the structure of E. coli bd-II type oxidase with the bound inhibitor aurachin D, providing a structural basis for the design of specifically binding antibiotics.

Bibliographic Details
Main Authors: Antonia Grauel, Jan Kägi, Tim Rasmussen, Iryna Makarchuk, Sabrina Oppermann, Aurélien F. A. Moumbock, Daniel Wohlwend, Rolf Müller, Frederic Melin, Stefan Günther, Petra Hellwig, Bettina Böttcher, Thorsten Friedrich
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26835-2

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