Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial

Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial

Background Coronary artery disease (CAD) is a leading cause of death among the 38.4 million people with HIV globally. The extent to which cardiovascular polygenic risk scores (PRSs) derived in non‐HIV populations generalize to people with HIV is not well understood. Methods and Results PRSs for CAD...

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Bibliographic Details
Main Authors: Roger S. Zou, Yunfeng Ruan, Buu Truong, Romit Bhattacharya, Michael T. Lu, Júlia Karády, Rachel Bernardo, Phoebe Finneran, Whitney Hornsby, Kathleen V. Fitch, Heather J. Ribaudo, Markella V. Zanni, Pamela S. Douglas, Steven K. Grinspoon, Aniruddh P. Patel, Pradeep Natarajan
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
coronary CT angiography
people with HIV
polygenic risk scores
subclinical atherosclerosis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.033413

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