Co-culture of oligodendrocytes and neurons can be used to assess drugs for axon regeneration in the central nervous system

Co-culture of oligodendrocytes and neurons can be used to assess drugs for axon regeneration in the central nervous system

We present a novel in vitro model in which to investigate the efficacy of experimental drugs for the promotion of axon regeneration in the central nervous system. We co-cultured rat hippocampal neurons and cerebral cortical oligodendrocytes, and tested the co-culture system using a Nogo-66 receptor...

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Bibliographic Details
Main Authors: Lin Gang, Yu-chen Yao, Ying-fu Liu, Yi-peng Li, Kai Yang, Lei Lu, Yuan-chi Cheng, Xu-yi Chen, Yue Tu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; experimental models; NEP1-40; oligodendrocytes; neurons; axon regeneration; Nogo; PC12 cells; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=10;spage=1612;epage=1616;aulast=Gang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=10;spage=1612;epage=1616;aulast=Gang

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