Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors

Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors

In vivo axon pathfinding mechanisms in the neuron-dense brain remain relatively poorly characterized. We study the Drosophila mushroom body (MB) axons, whose α and β branches connect to different brain areas. We show that the Ryk family WNT5 receptor, DRL (derailed), which is expressed in the dorsom...

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Bibliographic Details
Main Authors: Elodie Reynaud, Liza L. Lahaye, Ana Boulanger, Iveta M. Petrova, Claire Marquilly, Adrien Flandre, Tania Martianez, Martin Privat, Jasprina N. Noordermeer, Lee G. Fradkin, Jean-Maurice Dura
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715004362

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http://www.sciencedirect.com/science/article/pii/S2211124715004362

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