Associations between Bone Mineral Density and Longitudinal Changes of Vertebral Bone Marrow and Paraspinal Muscle Composition Assessed Using MR-Based Proton Density Fat Fraction and T2* Maps in Patients with and without Osteoporosis

Associations between Bone Mineral Density and Longitudinal Changes of Vertebral Bone Marrow and Paraspinal Muscle Composition Assessed Using MR-Based Proton Density Fat Fraction and T2* Maps in Patients with and without Osteoporosis

Background: Proton-density fat fraction (PDFF) and T2* of the vertebrae, as well as the cross-sectional area (CSA) of the paraspinal musculature (PSM), have been suggested as biomarkers for bone fragility. The aim of this study was to longitudinally assess changes in PDFF, T2* and CSA of the PSM ove...

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Main Authors: Florian Tilman Gassert, Leander Glanz, Christof Boehm, Jonathan Stelter, Felix Gerhard Gassert, Yannik Leonhardt, Georg C. Feuerriegel, Markus Graf, Markus Wurm, Thomas Baum, Rickmer F. Braren, Benedikt J. Schwaiger, Marcus R. Makowski, Dimitrios Karampinos, Alexandra S. Gersing
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Diagnostics
Subjects:
osteoporosis
magnetic resonance imaging
spine
bone marrow
Online Access:https://www.mdpi.com/2075-4418/12/10/2467

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