Human Single-Chain Antibodies That Neutralize Elastolytic Activity of <i>Pseudomonas aeruginosa</i> LasB

Human Single-Chain Antibodies That Neutralize Elastolytic Activity of <i>Pseudomonas aeruginosa</i> LasB

LasB (elastase/pseudolysin) is an injurious zinc-metalloprotease secreted by the infecting <i>Pseudomonas aeruginosa</i>. LasB is recognized as the bacterial key virulence factor for establishment of successful infection, acquisition of nutrients, dissemination, tissue invasion, and immu...

Full description

Bibliographic Details
Main Authors:	Sirijan Santajit, Thida Kong-ngoen, Manas Chongsa-Nguan, Usa Boonyuen, Pornpan Pumirat, Nitat Sookrung, Wanpen Chaicumpa, Nitaya Indrawattana
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Pathogens
Subjects:	elastase elastolytic activity human single-chain antibody HuscFv <i>Pseudomonas aeruginosa</i> LasB
Online Access:	https://www.mdpi.com/2076-0817/10/6/765

Similar Items

Human Single-chain Variable Fragments Neutralize Pseudomonas aeruginosa Quorum Sensing Molecule, 3O-C12-HSL, and Prevent Cells From the HSL-mediated Apoptosis
by: Sirijan Santajit, et al.
Published: (2020-06-01)

Antimicrobial Resistance and Virulence of Non-Typhoidal <i>Salmonella</i> from Retail Foods Marketed in Bangkok, Thailand
by: Thida Kong-Ngoen, et al.
Published: (2022-02-01)

Ophiophagus hannah Venom: Proteome, Components Bound by Naja kaouthia Antivenin and Neutralization by N. kaouthia Neurotoxin-Specific Human ScFv
by: Witchuda Danpaiboon, et al.
Published: (2014-05-01)

Human super antibody to viral RNA-dependent RNA polymerase produced by a modified Sortase self-cleave-bacteria surface display system
by: Kantaphon Glab-ampai, et al.
Published: (2023-12-01)

Engineered Human Monoclonal scFv to Receptor Binding Domain of <i>Ebolavirus</i>
by: Jaslan Densumite, et al.
Published: (2021-05-01)

Human Monoclonal scFvs that Neutralize Fribrinogenolytic Activity of Kaouthiagin, a Zinc-Metalloproteinase in Cobra (<i>Naja kaouthia</i>) Venom
by: Jirawat Khanongnoi, et al.
Published: (2018-12-01)

Human Transbodies to Reverse Transcriptase Connection Subdomain of HIV-1 Gag-Pol Polyprotein Reduce Infectiousness of the Virus Progeny
by: Watee Seesuay, et al.
Published: (2021-08-01)

Occurrence, antimicrobial resistance, virulence, and biofilm formation capacity of Vibrio spp. and Aeromonas spp. isolated from raw seafood marketed in Bangkok, Thailand
by: Sirijan Santajit, et al.
Published: (2022-07-01)

Human Superantibodies to 3CL<sup>pro</sup> Inhibit Replication of SARS-CoV-2 across Variants
by: Kittirat Glab-ampai, et al.
Published: (2022-06-01)

Strict Anatomical Colocalization of Vitiligo and Elastolytic Granulomas
by: N. Merino de Paz, et al.
Published: (2010-02-01)

Development of a Rapid Reverse Transcription-Recombinase Polymerase Amplification Couple Nucleic Acid Lateral Flow Method for Detecting Porcine Epidemic Diarrhoea Virus
by: Seatthanan Pewlaoo, et al.
Published: (2022-07-01)

Quorum Sensing in ESKAPE Bugs: A Target for Combating Antimicrobial Resistance and Bacterial Virulence
by: Sirijan Santajit, et al.
Published: (2022-10-01)

Clinical and morphological features of elastolytic granulomas
by: A. V. Patrushev, et al.
Published: (2017-08-01)

DNA Sequences of LasB Gene in Pseudomonas aeruginosa Isolated from Some Clinical Cases
by: Rana M. A. Al-Shwaikh
Published: (2017-03-01)

OPTIMIZATION OF ELASTOLYTIC PEPTIDASE BIOSYNTHESIS BY Bacillus thuringiensis ІМV В-7324
by: Nidialkova N. А., et al.
Published: (2014-10-01)

A Retrospective Study of 105 Patients with Elastolytic Giant Cell Granuloma and a Proposal for a New Clinical Classification
by: Yue-Tong Qian, et al.
Published: (2022-03-01)

A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
by: Xiaoping Liu, et al.
Published: (2018-06-01)

Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1
by: Thunchanok Rukkawattanakul, et al.
Published: (2017-02-01)

Phenotypic and Genotypic Investigation of Carbapenem-Resistant <i>Acinetobacter baumannii</i> in Maharaj Nakhon Si Thammarat Hospital, Thailand
by: Sirijan Santajit, et al.
Published: (2023-03-01)

Annular elastolytic giant cell granuloma in association with Hashimoto's thyroiditis
by: Rishi Hassan, et al.
Published: (2016-01-01)

Molecular feature of lasB gene of Pseudomonas aeruginosa isolated from different clinical sources
by: Khwam R Hussein
Published: (2019-04-01)

Molecular feature of lasB gene of Pseudomonas aeruginosa isolated from different clinical sources
by: Khwam R Hussein
Published: (2019-04-01)

Molecular feature of lasB gene of Pseudomonas aeruginosa isolated from different clinical sources
by: Khwam R Hussein
Published: (2019-04-01)

Annualr elastolytic giant cell granuloma with penile involvement
by: Sengupta Sujata, et al.
Published: (2006-01-01)

Clinical Strains of Pseudomonas aeruginosa Secrete LasB Elastase to Induce Hemorrhagic Diffuse Alveolar Damage in Mice
by: Zhu Y, et al.
Published: (2021-08-01)

Staphylococcus spp. associated with subclinical bovine mastitis in central and northeast provinces of Thailand
by: Natapol Pumipuntu, et al.
Published: (2019-03-01)

Detection and drug resistance profile of Escherichia coli from subclinical mastitis cows and water supply in dairy farms in Saraburi Province, Thailand
by: Woranich Hinthong, et al.
Published: (2017-06-01)

GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus
by: Nitaya Indrawattana, et al.
Published: (2022-01-01)

Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation
by: Fabien Bastaert, et al.
Published: (2018-07-01)

Effect of Satureja khuzistanica essential oil (SKEO) extract on expression of lasA and lasB genes in Pseudomonas aeruginosa
by: Davoud Iman Islamieh, et al.
Published: (2019-03-01)

Toxic Marine Puffer Fish in Thailand Seas and Tetrodotoxin They Contained
by: Hisao Kurazono, et al.
Published: (2011-10-01)

The Structures and Binding Modes of Small-Molecule Inhibitors of <i>Pseudomonas aeruginosa</i> Elastase LasB
by: Virgyl Camberlein, et al.
Published: (2022-08-01)

Antibiotic Resistance Genes Among Carbapenem-resistant Enterobacterales (CRE) Isolates of Prapokklao Hospital, Chanthaburi Province, Thailand
by: Tunyong W, et al.
Published: (2021-08-01)

Occurrence of antimicrobial resistance and antimicrobial resistance genes in methicillin-resistant Staphylococcus aureus isolated from healthy rabbits
by: Arunee Jangsangthong, et al.
Published: (2022-11-01)

Screening method for Staphylococcus aureus identification in subclinical bovine mastitis from dairy farms
by: Natapol Pumipuntu, et al.
Published: (2017-07-01)

Genetic Diagnosis of tox A and las B Genes in Pseudomonas aeruginosa isolated from different clinical sources.
by: Mohammed E. Altaai, et al.
Published: (2017-12-01)

Altered proteome of a Burkholderia pseudomallei mutant defective in short-chain dehydrogenase affects cell adhesion, biofilm formation and heat stress tolerance
by: Onrapak Reamtong, et al.
Published: (2020-03-01)

Engineered Fully Human Single-Chain Monoclonal Antibodies to PIM2 Kinase
by: Kanasap Kaewchim, et al.
Published: (2021-10-01)

Annular elastolytic giant cell granuloma in a patient with Ehlers–Danlos syndrome
by: Tatiana A. Gaydina, et al.
Published: (2022-09-01)

Phylogenetic analysis and antibiotic resistance of Escherichia coli isolated from wild and domestic animals at an agricultural land interface area of Salaphra wildlife sanctuary, Thailand
by: Taksaon Duangurai, et al.
Published: (2022-12-01)