Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation
Abstract Background Cough suppression assessed by embarrassment about coughing has been shown in adolescents with cystic fibrosis (CF) and negatively affects health-related quality of life (HRQoL) and clinical indicators of disease severity in adolescent females. However, whether cough suppression e...
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | Health and Quality of Life Outcomes |
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| Online Access: | https://doi.org/10.1186/s12955-022-02053-2 |
| _version_ | 1828194537089007616 |
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| author | Ute Niehammer Mathis Steindor Svenja Straßburg Sivagurunathan Sutharsan Christian Taube Matthias Welsner Raphael Hirtz Florian Stehling |
| author_facet | Ute Niehammer Mathis Steindor Svenja Straßburg Sivagurunathan Sutharsan Christian Taube Matthias Welsner Raphael Hirtz Florian Stehling |
| author_sort | Ute Niehammer |
| collection | DOAJ |
| description | Abstract Background Cough suppression assessed by embarrassment about coughing has been shown in adolescents with cystic fibrosis (CF) and negatively affects health-related quality of life (HRQoL) and clinical indicators of disease severity in adolescent females. However, whether cough suppression exists in adults has been studied as little as its effects on clinical and psychological outcomes beyond adolescence. Methods Seventy-one subjects completed the self-reported 'Cystic Fibrosis Questionnaire-Revised (CFQ-R + 14)' and a self-report questionnaire about cough suppression, health-related perspectives, and therapy adherence. The status of CF disease was quantified in terms of the percentage of predicted forced expiratory volume in one second (ppFEV1), body mass index (BMI), Pseudomonas aeruginosa, pancreatic status, and CF-related diabetes (CFRD). Additional demographic data for sex, age, graduation, employment, and marital status were assessed. Results CS exists in adult CF and is associated with impaired HRQoL but not the overall CF disease status regarding BMI, ppFEV1, or health-related perspectives. Despite a higher prevalence of cough suppression in women, no effect of sex regarding either outcome measure was observed. Conclusion The results of this study suggest that mental health indicators have an impact on cough suppression. |
| first_indexed | 2024-04-12T09:27:38Z |
| format | Article |
| id | doaj.art-2010a8c64b6c44f19f441d6d28554327 |
| institution | Directory Open Access Journal |
| issn | 1477-7525 |
| language | English |
| last_indexed | 2024-04-12T09:27:38Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Health and Quality of Life Outcomes |
| spelling | doaj.art-2010a8c64b6c44f19f441d6d285543272022-12-22T03:38:27ZengBMCHealth and Quality of Life Outcomes1477-75252022-10-012011810.1186/s12955-022-02053-2Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlationUte Niehammer0Mathis Steindor1Svenja Straßburg2Sivagurunathan Sutharsan3Christian Taube4Matthias Welsner5Raphael Hirtz6Florian Stehling7Department of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-EssenPaediatric Pulmonology and Sleep Medicine, Children’s Hospital, University of Duisburg-EssenDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-EssenDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-EssenDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-EssenDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-EssenPaediatric Endocrinology, Children’s Hospital, University of Duisburg-EssenPaediatric Pulmonology and Sleep Medicine, Children’s Hospital, University of Duisburg-EssenAbstract Background Cough suppression assessed by embarrassment about coughing has been shown in adolescents with cystic fibrosis (CF) and negatively affects health-related quality of life (HRQoL) and clinical indicators of disease severity in adolescent females. However, whether cough suppression exists in adults has been studied as little as its effects on clinical and psychological outcomes beyond adolescence. Methods Seventy-one subjects completed the self-reported 'Cystic Fibrosis Questionnaire-Revised (CFQ-R + 14)' and a self-report questionnaire about cough suppression, health-related perspectives, and therapy adherence. The status of CF disease was quantified in terms of the percentage of predicted forced expiratory volume in one second (ppFEV1), body mass index (BMI), Pseudomonas aeruginosa, pancreatic status, and CF-related diabetes (CFRD). Additional demographic data for sex, age, graduation, employment, and marital status were assessed. Results CS exists in adult CF and is associated with impaired HRQoL but not the overall CF disease status regarding BMI, ppFEV1, or health-related perspectives. Despite a higher prevalence of cough suppression in women, no effect of sex regarding either outcome measure was observed. Conclusion The results of this study suggest that mental health indicators have an impact on cough suppression.https://doi.org/10.1186/s12955-022-02053-2Cystic fibrosisAdultsCough suppressionHealth-related quality of lifeSex differencesClinical outcomes |
| spellingShingle | Ute Niehammer Mathis Steindor Svenja Straßburg Sivagurunathan Sutharsan Christian Taube Matthias Welsner Raphael Hirtz Florian Stehling Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation Health and Quality of Life Outcomes Cystic fibrosis Adults Cough suppression Health-related quality of life Sex differences Clinical outcomes |
| title | Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation |
| title_full | Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation |
| title_fullStr | Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation |
| title_full_unstemmed | Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation |
| title_short | Cough suppression and HRQoL in adult people with cystic fibrosis: an unexplored correlation |
| title_sort | cough suppression and hrqol in adult people with cystic fibrosis an unexplored correlation |
| topic | Cystic fibrosis Adults Cough suppression Health-related quality of life Sex differences Clinical outcomes |
| url | https://doi.org/10.1186/s12955-022-02053-2 |
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