The Emergence of Novel Sequence Type Strains Reveals an Evolutionary Process of Intraspecies Clone Shifting in ICU-Spreading Carbapenem-Resistant Klebsiella pneumoniae
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an urgent public health problem worldwide, and its rapid evolution in the clinical environment has been a major concern. A total of 99 CRKP isolates spreading in the intensive care unit (ICU) setting were included and subjected to whole-genome seq...
Main Authors: | Dongdong Zhao, Qiucheng Shi, Dandan Hu, Li Fang, Yihan Mao, Peng Lan, Xinhong Han, Ping Zhang, Huangdu Hu, Yanfei Wang, Jingjing Quan, Yunsong Yu, Yan Jiang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2021.691406/full |
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