Changes of Host Immunity Mediated by IFN-γ<sup>+</sup> CD8<sup>+</sup> T Cells in Children with Adenovirus Pneumonia in Different Severity of Illness

Changes of Host Immunity Mediated by IFN-γ<sup>+</sup> CD8<sup>+</sup> T Cells in Children with Adenovirus Pneumonia in Different Severity of Illness

The host immunity of patients with adenovirus pneumonia in different severity of illness is unclear. This study compared the routine laboratory tests and the host immunity of human adenovirus (HAdV) patients with different severity of illness. A co-cultured cell model in vitro was established to ver...

Full description

Bibliographic Details
Main Authors:	Ruilin Zheng, Yinghua Li, Danyang Chen, Jingyao Su, Ning Han, Haitian Chen, Zhihui Ning, Misi Xiao, Mingqi Zhao, Bing Zhu
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Viruses
Subjects:	HAdV T cells cytokine adenovirus pneumonia
Online Access:	https://www.mdpi.com/1999-4915/13/12/2384

Similar Items

A prediction model for acute respiratory distress syndrome in immunocompetent adults with adenovirus-associated Pneumonia: a multicenter retrospective analysis
by: Fengyu Lin, et al.
Published: (2023-11-01)

Longitudinal Analysis of Binding Antibody Levels Against 39 Human Adenovirus Types in Sera from 60 Regular Blood Donors from Greifswald, Germany, over 5 Years from 2018 to 2022
by: Xiaoyan Wang, et al.
Published: (2024-11-01)

Monocyte count is associated with the severity of human adenovirus pneumonia in hospitalized children aged less than 6 years
by: Rong Hu, et al.
Published: (2023-02-01)

Differential Genome Replication of a Unique Single-Amino-Acid Mutation in the Adenovirus-4 Component of the Live Oral Adenovirus Type 4 and Type 7 Vaccine
by: Natalie D. Collins, et al.
Published: (2023-06-01)

A Fulminant Case of Adenovirus Genotype C108 Infection in a Pediatric Stem Cell Transplant Recipient with x-Linked Lymphoproliferative Syndrome Type 1
by: Bradford A. Becken, et al.
Published: (2024-01-01)

Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression
by: Lilian Göttig, et al.
Published: (2023-06-01)

DMSO and Its Role in Differentiation Impact Efficacy of Human Adenovirus (HAdV) Infection in HepaRG Cells
by: Katharina Hofmann, et al.
Published: (2024-04-01)

Preliminary Data Related to the Effect of Climacostol Produced by the Freshwater Ciliate <i>Climacostomum virens</i> on Human Adenovirus
by: Marco Verani, et al.
Published: (2020-06-01)

High-Frequency Recombination of Human Adenovirus in Children with Acute Respiratory Tract Infections in Beijing, China
by: Fangming Wang, et al.
Published: (2024-05-01)

Molecular characterization of human adenovirus associated with pediatric severe acute respiratory infections in a tertiary care hospital in North East India
by: Reema Nath, et al.
Published: (2024-10-01)

Fatal Neonatal Sepsis Associated with Human Adenovirus Type 56 Infection: Genomic Analysis of Three Recent Cases Detected in the United States
by: William R. Otto, et al.
Published: (2021-06-01)

Seroprevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Patients with Neuromuscular Disorders
by: Patrick Julian Klann, et al.
Published: (2022-12-01)

Human Adenovirus Entry and Early Events during Infection of Primary Murine Neurons: Immunofluorescence Studies In Vitro
by: Anna Słońska, et al.
Published: (2024-02-01)

Adeno-Associated Virus 2 and Human Adenovirus F41 in Wastewater during Outbreak of Severe Acute Hepatitis in Children, Ireland
by: Niamh A. Martin, et al.
Published: (2023-04-01)

Current antiviral agents against human adenoviruses associated with respiratory infections
by: Lexi Li, et al.
Published: (2024-08-01)

Animal Models in Human Adenovirus Research
by: Luca D. Bertzbach, et al.
Published: (2021-12-01)

E4orf1: The triple agent of adenovirus – Unraveling its roles in oncogenesis, infectious obesity and immune responses in virus replication and vector therapy
by: Lilian Göttig, et al.
Published: (2024-06-01)

Human adenovirus DNA polymerase is evolutionarily and functionally associated with human telomerase reverse transcriptase based on in silico molecular characterization that implicate abacavir and zidovudine
by: Toluwase Hezekiah Fatoki
Published: (2023-06-01)

A seroepidemiological survey of adenovirus type 7 circulation among healthy adults in China and in Sierra Leone, West Africa
by: Busen Wang, et al.
Published: (2023-02-01)

Human adenovirus type 3 restores pharmacologically inhibited exosomal cargo in lung carcinoma cells
by: Ayodeji O. Ipinmoroti, et al.
Published: (2024-02-01)

Translational selenium nanoparticles boost GPx1 activation to reverse HAdV-14 virus-induced oxidative damage
by: Yinghua Li, et al.
Published: (2024-08-01)

Hybrid sequencing for detailed genetic characterization of human adenoviruses
by: Bin Fang, et al.
Published: (2024-11-01)

Pathogenicity and virulence of human adenovirus F41: Possible links to severe hepatitis in children
by: Roger J. Grand
Published: (2023-12-01)

The protein composition of human adenovirus replication compartments
by: Paloma Hidalgo, et al.
Published: (2025-01-01)

Development of Oncolytic Vectors Based on Human Adenovirus Type 6 for Cancer Treatment
by: Ivan D. Osipov, et al.
Published: (2023-01-01)

Comparative analysis of the impact of 40 adenovirus types on dendritic cell activation and CD8+ T cell proliferation capacity for the identification of favorable immunization vector candidates
by: Xiaoyan Wang, et al.
Published: (2023-10-01)

Adenovirus E1B-55K interferes with cellular IκB kinase complex subunit proteins
by: Wing-Hang Ip, et al.
Published: (2025-03-01)

Human adenovirus type 7 (HAdV-7) infection induces pulmonary vascular endothelial injury through the activation of endothelial autophagy
by: Zhihe Chen, et al.
Published: (2024-12-01)

Antiviral Activity of a Cyclic Pro-Pro-<i>β<sup>3</sup></i>-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5
by: Ewa Zaczyńska, et al.
Published: (2022-05-01)

A humanized anti-human adenovirus 55 monoclonal antibody with good neutralization ability
by: Lei Chen, et al.
Published: (2023-03-01)

The adenoviral E4orf3/4 is a regulatory polypeptide with cell transforming properties in vitro
by: Wing-Hang Ip, et al.
Published: (2023-06-01)

Role of Cytokines, Chemokines and IFN-γ<sup>+</sup> IL-17<sup>+</sup> Double-Positive CD4<sup>+</sup> T Cells in Patients with Multiple Sclerosis
by: Marlos Aureliano Dias de Sousa, et al.
Published: (2022-08-01)

Post-COVID sequelae effect in chronic fatigue syndrome: SARS-CoV-2 triggers latent adenovirus in the oral mucosa
by: Ulf Hannestad, et al.
Published: (2023-06-01)

Evaluation of qPCR for the Selective Detection of Enteric Adenovirus Followed by Sequence-Based Genetic Characterization of F Strains Circulating in Brazil
by: Lilian Gonçalves do Nascimento, et al.
Published: (2024-06-01)

Breaking Entry-and Species Barriers: LentiBOOST<sup>®</sup> Plus Polybrene Enhances Transduction Efficacy of Dendritic Cells and Monocytes by Adenovirus 5
by: Astrid Strack, et al.
Published: (2022-01-01)

Ad6-Based GM-CSF Expressing Vector Displays Oncolytic and Immunostimulatory Effects in an Immunocompetent Syrian Hamster Model of Cholangiocarcinoma
by: Daria S. Zabelina, et al.
Published: (2025-01-01)

The Antiviral Activity of Trifluoromethylthiolane Derivatives
by: Liubov Artiukh, et al.
Published: (2022-11-01)

Balance of CD4<sup>+</sup>IFNγ+ and CD4<sup>+</sup>CD25<sup>hi</sup>T cells as early predictor of a 3-month outcome in ischemic stroke patients
by: S. A. Morozov, et al.
Published: (2020-08-01)

A Novel H-2<sup>d</sup> Epitope for Influenza A Polymerase Acidic Protein
by: Ida Uddbäck, et al.
Published: (2022-03-01)

Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes<sup>+</sup> Thymic Innate CD8 T Cells
by: Hee Yeun Won, et al.
Published: (2023-10-01)