Single-cell transcriptome reveals diversity of Müller cells with different metabolic-mitochondrial signatures in normal and degenerated macula

Single-cell transcriptome reveals diversity of Müller cells with different metabolic-mitochondrial signatures in normal and degenerated macula

Müller cell is the most abundant glial cell in mammalian retina, supporting the functions of photoreceptors and other retinal neurons via maintaining environmental homeostasis. In response to injury and/or neuronal degeneration, Müller cells undergo morphological and functional alternations, known a...

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Bibliographic Details
Main Authors:	Bei Liu, Jiali He, Ling Zhong, Lulin Huang, Bo Gong, Jing Hu, Hao Qian, Zhenglin Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Neuroscience
Subjects:	Müller cell mitochondrial function age-related macular degeneration gliosis macula
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2022.1079498/full

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