Bioactive engineered scaffolds based on PCL-PEG-PCL and tumor cell-derived exosomes to minimize the foreign body reaction

Bioactive engineered scaffolds based on PCL-PEG-PCL and tumor cell-derived exosomes to minimize the foreign body reaction

Long-term presence of M1 macrophages causes serious foreign body reaction (FBR), which is the main reason for the failure of biological scaffold integration. Inducing M2 polarization of macrophages near scaffolds to reduce foreign body response has been widely researched. In this work, inspired by t...

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Bibliographic Details
Main Authors: Zehong Xiang, Xinghua Guan, Zhifang Ma, Qiang Shi, Mikhail Panteleev, Fazly I. Ataullakhanov
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Biomaterials and Biosystems
Subjects:
Exosomes
Macrophages
Inflammation
Polarization
Engineered scaffolds
Online Access:http://www.sciencedirect.com/science/article/pii/S2666534422000174

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