Personalized Medicine: Pharmacogenomics and Drug Development

Personalized medicine aims is to supply the proper drug to the proper patient within the right dose. Pharmacogenomics (PGx) is to recognize genetic variants that may influence drug efficacy and toxicity. All things considered, the fields cover a wide area, including basic drug discovery researches,...

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Main Authors: Somayeh Mirsadeghi, Bagher Larijani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-03-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/6211
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author Somayeh Mirsadeghi
Bagher Larijani
author_facet Somayeh Mirsadeghi
Bagher Larijani
author_sort Somayeh Mirsadeghi
collection DOAJ
description Personalized medicine aims is to supply the proper drug to the proper patient within the right dose. Pharmacogenomics (PGx) is to recognize genetic variants that may influence drug efficacy and toxicity. All things considered, the fields cover a wide area, including basic drug discovery researches, the genetic origin of pharmacokinetics and pharmacodynamics, novel drug improvement, patient genetic assessment and clinical patient administration. At last, the objective of Pharmacogenomics is to anticipate a patient’s genetic response to a particular drug as a way of presenting the best possible medical treatment. By predicting the drug response of an individual, it will be possible to increase the success of therapies and decrease the incidence of adverse side effect.
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spelling doaj.art-201fab6acfa7450e996cfb2eecaeae432022-12-21T21:17:34ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942017-03-015535131Personalized Medicine: Pharmacogenomics and Drug DevelopmentSomayeh Mirsadeghi0Bagher Larijani1Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.Personalized medicine aims is to supply the proper drug to the proper patient within the right dose. Pharmacogenomics (PGx) is to recognize genetic variants that may influence drug efficacy and toxicity. All things considered, the fields cover a wide area, including basic drug discovery researches, the genetic origin of pharmacokinetics and pharmacodynamics, novel drug improvement, patient genetic assessment and clinical patient administration. At last, the objective of Pharmacogenomics is to anticipate a patient’s genetic response to a particular drug as a way of presenting the best possible medical treatment. By predicting the drug response of an individual, it will be possible to increase the success of therapies and decrease the incidence of adverse side effect.https://acta.tums.ac.ir/index.php/acta/article/view/6211Personalized medicinePharmacogeneticsDrug discoveryDrug safety
spellingShingle Somayeh Mirsadeghi
Bagher Larijani
Personalized Medicine: Pharmacogenomics and Drug Development
Acta Medica Iranica
Personalized medicine
Pharmacogenetics
Drug discovery
Drug safety
title Personalized Medicine: Pharmacogenomics and Drug Development
title_full Personalized Medicine: Pharmacogenomics and Drug Development
title_fullStr Personalized Medicine: Pharmacogenomics and Drug Development
title_full_unstemmed Personalized Medicine: Pharmacogenomics and Drug Development
title_short Personalized Medicine: Pharmacogenomics and Drug Development
title_sort personalized medicine pharmacogenomics and drug development
topic Personalized medicine
Pharmacogenetics
Drug discovery
Drug safety
url https://acta.tums.ac.ir/index.php/acta/article/view/6211
work_keys_str_mv AT somayehmirsadeghi personalizedmedicinepharmacogenomicsanddrugdevelopment
AT bagherlarijani personalizedmedicinepharmacogenomicsanddrugdevelopment