Periodontitis and oral human papillomavirus infection among Hispanic adults
Introduction: Research on the association between periodontitis and oral human papilloma virus (HPV) infection is inconsistent. The cross-sectional association of severe periodontitis with oral HPV infection was investigated in a sample of Hispanic adults. Methods: Data from the 2014–2016 San Juan O...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-06-01
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| Series: | Papillomavirus Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405852117300927 |
| _version_ | 1818842381963755520 |
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| author | Ana Patricia Ortiz Daisy González José Vivaldi-Oliver Maira Castañeda Vivian Rivera Elba Díaz Hilmaris Centeno Cristina Muñoz Joel Palefsky Kaumudi Joshipura Cynthia M. Pérez |
| author_facet | Ana Patricia Ortiz Daisy González José Vivaldi-Oliver Maira Castañeda Vivian Rivera Elba Díaz Hilmaris Centeno Cristina Muñoz Joel Palefsky Kaumudi Joshipura Cynthia M. Pérez |
| author_sort | Ana Patricia Ortiz |
| collection | DOAJ |
| description | Introduction: Research on the association between periodontitis and oral human papilloma virus (HPV) infection is inconsistent. The cross-sectional association of severe periodontitis with oral HPV infection was investigated in a sample of Hispanic adults. Methods: Data from the 2014–2016 San Juan Overweight Adults Longitudinal Study (n = 740) was analyzed. Periodontitis assessment and self-collection of oral HPV samples followed the National Health and Nutrition Examination Survey methodology. Periodontitis was defined using the Centers of Disease Control and Prevention/American Academy of Periodontology definition. HPV typing was performed using polymerase chain reaction. Multivariate logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs). Results: 5.7% of participants had oral HPV infection and 20.3% had severe periodontitis. Adults with severe periodontitis had higher odds of oral HPV infection than those with none/mild disease (OR=2.9, 95% CI: 1.0–8.4, p < 0.05) in multivariable analysis. Adults with clinical attachment loss≥ 7 mm and pocket depth PD≥ 6 mm had 2- to 3-fold higher odds of HPV infection. Conclusions: Severe periodontitis was positively associated to oral HPV infection. Longitudinal evaluation of periodontal inflammation's role in acquisition and persistence of oral HPV infection is needed, as periodontitis screening could identify individuals at increased risk of HPV-related oral malignancies. Keywords: Periodontitis, Oral HPV, Hispanics, Adults, Oral health, Puerto Rico |
| first_indexed | 2024-12-19T04:41:05Z |
| format | Article |
| id | doaj.art-20201ff5802a4c7d9b75973d30d9b9aa |
| institution | Directory Open Access Journal |
| issn | 2405-8521 |
| language | English |
| last_indexed | 2024-12-19T04:41:05Z |
| publishDate | 2018-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Papillomavirus Research |
| spelling | doaj.art-20201ff5802a4c7d9b75973d30d9b9aa2022-12-21T20:35:36ZengElsevierPapillomavirus Research2405-85212018-06-015128133Periodontitis and oral human papillomavirus infection among Hispanic adultsAna Patricia Ortiz0Daisy González1José Vivaldi-Oliver2Maira Castañeda3Vivian Rivera4Elba Díaz5Hilmaris Centeno6Cristina Muñoz7Joel Palefsky8Kaumudi Joshipura9Cynthia M. Pérez10Department of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, 00936-5067 San Juan, Puerto Rico; Cancer Control and Population Sciences Program, Puerto Rico Comprehensive Cancer Center, University of Puerto Rico, San Juan, Puerto Rico; Corresponding author at: Department of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, P.O. Box 363027, San Juan, PR 00936-3027, Puerto Rico.Department of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, 00936-5067 San Juan, Puerto RicoCenter for Clinical Research and Health Promotion, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto RicoDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, 00936-5067 San Juan, Puerto RicoDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, 00936-5067 San Juan, Puerto RicoCenter for Clinical Research and Health Promotion, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto RicoDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, 00936-5067 San Juan, Puerto RicoCancer Control and Population Sciences Program, Puerto Rico Comprehensive Cancer Center, University of Puerto Rico, San Juan, Puerto RicoDepartment of Infectious Diseases, School of Medicine, University of California, San Francisco (UCSF), United StatesCenter for Clinical Research and Health Promotion, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto RicoCancer Control and Population Sciences Program, Puerto Rico Comprehensive Cancer Center, University of Puerto Rico, San Juan, Puerto RicoIntroduction: Research on the association between periodontitis and oral human papilloma virus (HPV) infection is inconsistent. The cross-sectional association of severe periodontitis with oral HPV infection was investigated in a sample of Hispanic adults. Methods: Data from the 2014–2016 San Juan Overweight Adults Longitudinal Study (n = 740) was analyzed. Periodontitis assessment and self-collection of oral HPV samples followed the National Health and Nutrition Examination Survey methodology. Periodontitis was defined using the Centers of Disease Control and Prevention/American Academy of Periodontology definition. HPV typing was performed using polymerase chain reaction. Multivariate logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs). Results: 5.7% of participants had oral HPV infection and 20.3% had severe periodontitis. Adults with severe periodontitis had higher odds of oral HPV infection than those with none/mild disease (OR=2.9, 95% CI: 1.0–8.4, p < 0.05) in multivariable analysis. Adults with clinical attachment loss≥ 7 mm and pocket depth PD≥ 6 mm had 2- to 3-fold higher odds of HPV infection. Conclusions: Severe periodontitis was positively associated to oral HPV infection. Longitudinal evaluation of periodontal inflammation's role in acquisition and persistence of oral HPV infection is needed, as periodontitis screening could identify individuals at increased risk of HPV-related oral malignancies. Keywords: Periodontitis, Oral HPV, Hispanics, Adults, Oral health, Puerto Ricohttp://www.sciencedirect.com/science/article/pii/S2405852117300927 |
| spellingShingle | Ana Patricia Ortiz Daisy González José Vivaldi-Oliver Maira Castañeda Vivian Rivera Elba Díaz Hilmaris Centeno Cristina Muñoz Joel Palefsky Kaumudi Joshipura Cynthia M. Pérez Periodontitis and oral human papillomavirus infection among Hispanic adults Papillomavirus Research |
| title | Periodontitis and oral human papillomavirus infection among Hispanic adults |
| title_full | Periodontitis and oral human papillomavirus infection among Hispanic adults |
| title_fullStr | Periodontitis and oral human papillomavirus infection among Hispanic adults |
| title_full_unstemmed | Periodontitis and oral human papillomavirus infection among Hispanic adults |
| title_short | Periodontitis and oral human papillomavirus infection among Hispanic adults |
| title_sort | periodontitis and oral human papillomavirus infection among hispanic adults |
| url | http://www.sciencedirect.com/science/article/pii/S2405852117300927 |
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