Praxis-induced seizures in a patient with juvenile myoclonic epilepsy: MEG-EEG coregistration study

Purpose: Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures. Methods: A reflex myoclonic seizure was recorded by simultaneous magnetoence...

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Bibliographic Details
Main Authors: Sira Carrasco-García de León, Guiomar Niso, Leonidas Canuet, Laura Burriel-Lobo, Fernando Maestú, María Gudín Rodríguez-Magariños
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Epilepsy and Behavior Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213323215000420
Description
Summary:Purpose: Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures. Methods: A reflex myoclonic seizure was recorded by simultaneous magnetoencephalography (MEG) and electroencephalography (EEG) when a generalized spike–wave synchronous pattern at 3 Hz was observed. Results: Source reconstruction localized the epileptogenic area to the right premotor frontal cortex. Conclusions: The present study demonstrates that the origin of epileptiform activity in JME can be localized in brain areas associated with the premotor frontal cortex.
ISSN:2213-3232