Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials
ObjectiveThis study aimed to systematically review and meta-analyze the clinical efficacy of acceptance and commitment therapy (ACT) in patients with cancer and psychological distress.MethodsRandomized controlled trials (RCTs) from seven English electronic databases were systematically investigated...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1253266/full |
| _version_ | 1797365493376483328 |
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| author | Xing Jiang Jian Sun Ruiwen Song Ruiwen Song Yue Wang Jinglian Li Rongwei Shi |
| author_facet | Xing Jiang Jian Sun Ruiwen Song Ruiwen Song Yue Wang Jinglian Li Rongwei Shi |
| author_sort | Xing Jiang |
| collection | DOAJ |
| description | ObjectiveThis study aimed to systematically review and meta-analyze the clinical efficacy of acceptance and commitment therapy (ACT) in patients with cancer and psychological distress.MethodsRandomized controlled trials (RCTs) from seven English electronic databases were systematically investigated from inception to 3 October 2023. A total of 16 RCTs from 6 countries with 711 participants were included in this study. Estimated pooled effect sizes (ESs) were calculated via inverse-variance random-effects or fixed-effects (I2 ≤ 50%) model and presented by standardized mean difference (SMD). Subgroup analyses were performed to reduce confounding factors and heterogeneity, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used to evaluate the quality of the pooled ESs.ResultsThe pooled ESs revealed that statistically significant improvements in anxiety [postintervention SMD = −0.41 (95% confidence interval (CI), −0.71, −0.11); p = 0.008; I2 = 65%; follow-up SMD = −0.37 (95% CI, −0.66, −0.08); p = 0.01; I2 = 29%], depression [postintervention SMD = −0.45 (95% CI, −0.63, −0.27); p < 0.001; I2 = 49%; follow-up SMD = −0.52 (95% CI, −0.77, −0.28); p < 0.001; I2 = 0%], and psychological flexibility [postintervention SMD = −0.81 (95% CI, −1.50, −0.11); p = 0.02; I2 = 84%; follow-up SMD = −0.71 (95% CI, −1.12, −0.31); p = 0.0006; I2 = 38%] in ACT-treated participants were observed compared to patients treated with control conditions. However, other outcomes, such as physical symptom alleviation, were not significantly associated.ConclusionThe findings of this systematic review and meta-analysis suggest that ACT is associated with improvements in anxiety, depression, and psychological flexibility in patients with cancer.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022320515. |
| first_indexed | 2024-03-08T16:49:47Z |
| format | Article |
| id | doaj.art-2027524fbc32418bacb3006c5f3b143a |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-03-08T16:49:47Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-2027524fbc32418bacb3006c5f3b143a2024-01-05T04:43:42ZengFrontiers Media S.A.Frontiers in Psychology1664-10782024-01-011410.3389/fpsyg.2023.12532661253266Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trialsXing Jiang0Jian Sun1Ruiwen Song2Ruiwen Song3Yue Wang4Jinglian Li5Rongwei Shi6School of Nursing, Nanjing University of Chinese Medicine, Nanjing, ChinaSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, ChinaSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, ChinaDepartment of General Surgery, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, ChinaSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, ChinaSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, ChinaDepartment of Internal Medicine, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, ChinaObjectiveThis study aimed to systematically review and meta-analyze the clinical efficacy of acceptance and commitment therapy (ACT) in patients with cancer and psychological distress.MethodsRandomized controlled trials (RCTs) from seven English electronic databases were systematically investigated from inception to 3 October 2023. A total of 16 RCTs from 6 countries with 711 participants were included in this study. Estimated pooled effect sizes (ESs) were calculated via inverse-variance random-effects or fixed-effects (I2 ≤ 50%) model and presented by standardized mean difference (SMD). Subgroup analyses were performed to reduce confounding factors and heterogeneity, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used to evaluate the quality of the pooled ESs.ResultsThe pooled ESs revealed that statistically significant improvements in anxiety [postintervention SMD = −0.41 (95% confidence interval (CI), −0.71, −0.11); p = 0.008; I2 = 65%; follow-up SMD = −0.37 (95% CI, −0.66, −0.08); p = 0.01; I2 = 29%], depression [postintervention SMD = −0.45 (95% CI, −0.63, −0.27); p < 0.001; I2 = 49%; follow-up SMD = −0.52 (95% CI, −0.77, −0.28); p < 0.001; I2 = 0%], and psychological flexibility [postintervention SMD = −0.81 (95% CI, −1.50, −0.11); p = 0.02; I2 = 84%; follow-up SMD = −0.71 (95% CI, −1.12, −0.31); p = 0.0006; I2 = 38%] in ACT-treated participants were observed compared to patients treated with control conditions. However, other outcomes, such as physical symptom alleviation, were not significantly associated.ConclusionThe findings of this systematic review and meta-analysis suggest that ACT is associated with improvements in anxiety, depression, and psychological flexibility in patients with cancer.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022320515.https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1253266/fullacceptance and commitment therapyneoplasmscancerpsychological distressanxietysystematic review |
| spellingShingle | Xing Jiang Jian Sun Ruiwen Song Ruiwen Song Yue Wang Jinglian Li Rongwei Shi Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials Frontiers in Psychology acceptance and commitment therapy neoplasms cancer psychological distress anxiety systematic review |
| title | Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials |
| title_full | Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials |
| title_short | Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials |
| title_sort | acceptance and commitment therapy reduces psychological distress in patients with cancer a systematic review and meta analysis of randomized controlled trials |
| topic | acceptance and commitment therapy neoplasms cancer psychological distress anxiety systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1253266/full |
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