Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements
<p>Since its inception more than 2 decades ago, proton-transfer-reaction mass spectrometry (PTR-MS) has established itself as a powerful technique for the measurements of a wide range of volatile organic compounds (VOCs) with high time resolution and low detection limits and without the need f...
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| Format: | Article |
| Language: | English |
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Copernicus Publications
2023-03-01
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| Series: | Atmospheric Measurement Techniques |
| Online Access: | https://amt.copernicus.org/articles/16/1061/2023/amt-16-1061-2023.pdf |
| _version_ | 1811161188709433344 |
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| author | D. R. Worton S. Moreno S. Moreno K. O'Daly R. Holzinger |
| author_facet | D. R. Worton S. Moreno S. Moreno K. O'Daly R. Holzinger |
| author_sort | D. R. Worton |
| collection | DOAJ |
| description | <p>Since its inception more than 2 decades ago, proton-transfer-reaction mass spectrometry (PTR-MS) has established itself as a powerful technique for the measurements of a wide range of volatile
organic compounds (VOCs) with high time resolution and low detection limits
and without the need for any sample pre-treatment. As this technology has
matured and its application become more widespread, there is a growing need for accurate and traceable calibration to ensure measurement comparability.
As a result of the large number of VOCs detectable with PTR-MS, it is impractical to have a calibration standard or standards that cover all
observable compounds. However, recent work has demonstrated that
quantitative measurements of uncalibrated compounds are possible provided
that the transmission curve is accurately constrained. To enable this, a
novel traceable multi-component gas reference material containing 20
compounds spanning a mass range of 32 to 671 has been developed. The
development and compositional evolution of this reference material are described along with an evaluation of its accuracy and stability. This work
demonstrates that for the majority of components the accuracy is <span class="inline-formula"><</span> 5 % (most <span class="inline-formula"><</span> 3 %; <span class="inline-formula"><</span> 10 % for
hexamethylcyclotrisiloxane (D3-siloxane) and 1,2,4-trichlorobenzene – 1,2,4-TCB) with stabilities of <span class="inline-formula">></span> 2 years (<span class="inline-formula">></span> 1 year for acetonitrile, methanol and perfluorotributylamine – PFTBA).</p> |
| first_indexed | 2024-04-10T06:11:27Z |
| format | Article |
| id | doaj.art-202904d2727c4a7f98822c289b884ddb |
| institution | Directory Open Access Journal |
| issn | 1867-1381 1867-8548 |
| language | English |
| last_indexed | 2024-04-10T06:11:27Z |
| publishDate | 2023-03-01 |
| publisher | Copernicus Publications |
| record_format | Article |
| series | Atmospheric Measurement Techniques |
| spelling | doaj.art-202904d2727c4a7f98822c289b884ddb2023-03-02T14:48:38ZengCopernicus PublicationsAtmospheric Measurement Techniques1867-13811867-85482023-03-01161061107210.5194/amt-16-1061-2023Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurementsD. R. Worton0S. Moreno1S. Moreno2K. O'Daly3R. Holzinger4National Physical Laboratory, Hampton Road, Teddington, TW11 0LW, United KingdomNational Physical Laboratory, Hampton Road, Teddington, TW11 0LW, United Kingdomnow at: World Meteorological Organization (WMO), 7bis Avenue de la Paix, C.P. 2300, 1211, Geneva 2, SwitzerlandNational Physical Laboratory, Hampton Road, Teddington, TW11 0LW, United KingdomInstitute for Marine and Atmospheric Research, IMAU, Utrecht University, Utrecht, the Netherlands<p>Since its inception more than 2 decades ago, proton-transfer-reaction mass spectrometry (PTR-MS) has established itself as a powerful technique for the measurements of a wide range of volatile organic compounds (VOCs) with high time resolution and low detection limits and without the need for any sample pre-treatment. As this technology has matured and its application become more widespread, there is a growing need for accurate and traceable calibration to ensure measurement comparability. As a result of the large number of VOCs detectable with PTR-MS, it is impractical to have a calibration standard or standards that cover all observable compounds. However, recent work has demonstrated that quantitative measurements of uncalibrated compounds are possible provided that the transmission curve is accurately constrained. To enable this, a novel traceable multi-component gas reference material containing 20 compounds spanning a mass range of 32 to 671 has been developed. The development and compositional evolution of this reference material are described along with an evaluation of its accuracy and stability. This work demonstrates that for the majority of components the accuracy is <span class="inline-formula"><</span> 5 % (most <span class="inline-formula"><</span> 3 %; <span class="inline-formula"><</span> 10 % for hexamethylcyclotrisiloxane (D3-siloxane) and 1,2,4-trichlorobenzene – 1,2,4-TCB) with stabilities of <span class="inline-formula">></span> 2 years (<span class="inline-formula">></span> 1 year for acetonitrile, methanol and perfluorotributylamine – PFTBA).</p>https://amt.copernicus.org/articles/16/1061/2023/amt-16-1061-2023.pdf |
| spellingShingle | D. R. Worton S. Moreno S. Moreno K. O'Daly R. Holzinger Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements Atmospheric Measurement Techniques |
| title | Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements |
| title_full | Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements |
| title_fullStr | Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements |
| title_full_unstemmed | Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements |
| title_short | Development of an International System of Units (SI)-traceable transmission curve reference material to improve the quantitation and comparability of proton-transfer-reaction mass-spectrometry measurements |
| title_sort | development of an international system of units si traceable transmission curve reference material to improve the quantitation and comparability of proton transfer reaction mass spectrometry measurements |
| url | https://amt.copernicus.org/articles/16/1061/2023/amt-16-1061-2023.pdf |
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