The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019
Background: Regarding the availability of an effective vaccine against hepatitis B virus, global vaccination is the best cost-effective strategy to prevent HBV infection. However, some people may not respond to the vaccine or the titer of antibody decreases by time. Therefore, the present study ai...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Farname
2020-07-01
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| Series: | Iranian Journal of Medical Microbiology |
| Subjects: | |
| Online Access: | http://ijmm.ir/article-1-1106-en.html |
| _version_ | 1819009380662640640 |
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| author | Seyed Mohammad Ali Hashemi Fatemeh Hashemzadeh Helen Bahrampour Fatemeh Nekoei Negar Joharinia Jamal Sarvari |
| author_facet | Seyed Mohammad Ali Hashemi Fatemeh Hashemzadeh Helen Bahrampour Fatemeh Nekoei Negar Joharinia Jamal Sarvari |
| author_sort | Seyed Mohammad Ali Hashemi |
| collection | DOAJ |
| description | Background: Regarding the availability of an effective vaccine against hepatitis B virus, global vaccination is the best cost-effective strategy to prevent HBV infection. However, some people may not respond to the vaccine or the titer of antibody decreases by time. Therefore, the present study aimed to determine the frequency of anti-HBs antibody (anti-HBsAb), among university students in Fars province, southern Iran.
Methods: In this cross-sectional study, 825 medical students were enrolled. Blood samples were taken from the subjects, and the serum separated and stored at – 20 ºC until use. Next, HBs Ab titer was measured by ELISA method.
Results: Out of 825 students 54% was male and 46% were female. The mean age of the students was 19.5±1.9. The titer of anti-HBsAb in 529 (64%) of subjects was lower than 10 mIU/mL. Significant relationship was observed between age and the titer of anti-HBsAb (P=0.001), although no significant relationship was observed between gender (P=0.19), history of blood transfusion (P=0.58) and the titer of anti-HBsAb.
Conclusion: Finding of this study showed that the titer of anti-HBsAb in more than half of students was lower than 10 mIU/mL and by time the anti-HBsAb titer decreased, indicating the necessity of measurement of anti-HBsAb titer in medical students. |
| first_indexed | 2024-12-21T00:55:27Z |
| format | Article |
| id | doaj.art-202ff0340a444006aeebd051243940cb |
| institution | Directory Open Access Journal |
| issn | 1735-8612 2345-4342 |
| language | English |
| last_indexed | 2024-12-21T00:55:27Z |
| publishDate | 2020-07-01 |
| publisher | Farname |
| record_format | Article |
| series | Iranian Journal of Medical Microbiology |
| spelling | doaj.art-202ff0340a444006aeebd051243940cb2022-12-21T19:21:17ZengFarnameIranian Journal of Medical Microbiology1735-86122345-43422020-07-01144297306The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019Seyed Mohammad Ali Hashemi0Fatemeh Hashemzadeh1Helen Bahrampour2Fatemeh Nekoei3Negar Joharinia4Jamal Sarvari5 Department of Bacteriology & Virology, Shiraz University of Medical Sciences, Shiraz, Iran Department of Bacteriology & Virology, Shiraz University of Medical Sciences, Shiraz, Iran Department of Bacteriology & Virology, Shiraz University of Medical Sciences, Shiraz, Iran Department of Bacteriology & Virology, Shiraz University of Medical Sciences, Shiraz, Iran Department of Bacteriology & Virology, Shiraz University of Medical Sciences, Shiraz, Iran Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Background: Regarding the availability of an effective vaccine against hepatitis B virus, global vaccination is the best cost-effective strategy to prevent HBV infection. However, some people may not respond to the vaccine or the titer of antibody decreases by time. Therefore, the present study aimed to determine the frequency of anti-HBs antibody (anti-HBsAb), among university students in Fars province, southern Iran. Methods: In this cross-sectional study, 825 medical students were enrolled. Blood samples were taken from the subjects, and the serum separated and stored at – 20 ºC until use. Next, HBs Ab titer was measured by ELISA method. Results: Out of 825 students 54% was male and 46% were female. The mean age of the students was 19.5±1.9. The titer of anti-HBsAb in 529 (64%) of subjects was lower than 10 mIU/mL. Significant relationship was observed between age and the titer of anti-HBsAb (P=0.001), although no significant relationship was observed between gender (P=0.19), history of blood transfusion (P=0.58) and the titer of anti-HBsAb. Conclusion: Finding of this study showed that the titer of anti-HBsAb in more than half of students was lower than 10 mIU/mL and by time the anti-HBsAb titer decreased, indicating the necessity of measurement of anti-HBsAb titer in medical students.http://ijmm.ir/article-1-1106-en.htmlhepatitis b virusantibody titerstudentshiraz |
| spellingShingle | Seyed Mohammad Ali Hashemi Fatemeh Hashemzadeh Helen Bahrampour Fatemeh Nekoei Negar Joharinia Jamal Sarvari The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019 Iranian Journal of Medical Microbiology hepatitis b virus antibody titer student shiraz |
| title | The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019 |
| title_full | The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019 |
| title_fullStr | The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019 |
| title_full_unstemmed | The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019 |
| title_short | The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019 |
| title_sort | evaluation anti hbsab titer among university students in shiraz 2019 |
| topic | hepatitis b virus antibody titer student shiraz |
| url | http://ijmm.ir/article-1-1106-en.html |
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