Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia
The aim of this work is to know how to manage the complications of carbamazepine prescription following an essential trigeminal neuralgia (ETN). Essential trigeminal neuralgia is a syndrome of unilateral, paroxysmal, stabbing facial pain, originating from the trigeminal nerve. The age of onset is us...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-10-01
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| Series: | Advances in Oral and Maxillofacial Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667147622001224 |
| _version_ | 1811195811548102656 |
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| author | B. Zaher S. Bouzoubaa I. Ben Yahya |
| author_facet | B. Zaher S. Bouzoubaa I. Ben Yahya |
| author_sort | B. Zaher |
| collection | DOAJ |
| description | The aim of this work is to know how to manage the complications of carbamazepine prescription following an essential trigeminal neuralgia (ETN). Essential trigeminal neuralgia is a syndrome of unilateral, paroxysmal, stabbing facial pain, originating from the trigeminal nerve. The age of onset is usually between 40 and 60 years, most often in females with a global incidence of approximately 4–28.9 per 100,000 individuals. Many medical and surgical treatments are available. Most patients respond well to pharmacotherapy; carbamazepine and oxcarbazepine are first line therapy, while lamotrigine and baclofen are considered second line treatments. Other drugs such as gabapentin, pregabalin, and botulinum toxin-A are alternative treatments. Surgical interventions are reserved for patients who do not respond to adequate medical therapy. This work reports the case of a patient who was diagnosed with an ETN of the mandibular nerve (V3) and in whom carbamazepine was prescribed. A month and a half after the start of treatment, the patient presented with severe cutaneous-mucosal symptoms, which allowed us to evoke Stevens-Johnson syndrome as a complication to carbamazepine treatment. |
| first_indexed | 2024-04-12T00:50:02Z |
| format | Article |
| id | doaj.art-20337437d10b479790e687f64a2e44bb |
| institution | Directory Open Access Journal |
| issn | 2667-1476 |
| language | English |
| last_indexed | 2024-04-12T00:50:02Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Advances in Oral and Maxillofacial Surgery |
| spelling | doaj.art-20337437d10b479790e687f64a2e44bb2022-12-22T03:54:46ZengElsevierAdvances in Oral and Maxillofacial Surgery2667-14762022-10-018100372Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgiaB. Zaher0S. BouzoubaaI. Ben YahyaCorresponding author.The aim of this work is to know how to manage the complications of carbamazepine prescription following an essential trigeminal neuralgia (ETN). Essential trigeminal neuralgia is a syndrome of unilateral, paroxysmal, stabbing facial pain, originating from the trigeminal nerve. The age of onset is usually between 40 and 60 years, most often in females with a global incidence of approximately 4–28.9 per 100,000 individuals. Many medical and surgical treatments are available. Most patients respond well to pharmacotherapy; carbamazepine and oxcarbazepine are first line therapy, while lamotrigine and baclofen are considered second line treatments. Other drugs such as gabapentin, pregabalin, and botulinum toxin-A are alternative treatments. Surgical interventions are reserved for patients who do not respond to adequate medical therapy. This work reports the case of a patient who was diagnosed with an ETN of the mandibular nerve (V3) and in whom carbamazepine was prescribed. A month and a half after the start of treatment, the patient presented with severe cutaneous-mucosal symptoms, which allowed us to evoke Stevens-Johnson syndrome as a complication to carbamazepine treatment.http://www.sciencedirect.com/science/article/pii/S2667147622001224Trigeminal neuralgiaCarbamazepineTreatmentComplications |
| spellingShingle | B. Zaher S. Bouzoubaa I. Ben Yahya Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia Advances in Oral and Maxillofacial Surgery Trigeminal neuralgia Carbamazepine Treatment Complications |
| title | Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia |
| title_full | Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia |
| title_fullStr | Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia |
| title_full_unstemmed | Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia |
| title_short | Therapeutic management of carbamazepine's complications in front of essential trigeminal neuralgia |
| title_sort | therapeutic management of carbamazepine s complications in front of essential trigeminal neuralgia |
| topic | Trigeminal neuralgia Carbamazepine Treatment Complications |
| url | http://www.sciencedirect.com/science/article/pii/S2667147622001224 |
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