In silico integrative analysis of multi-omics reveals regulatory layers for diurnal gene expression in mouse liver

In silico integrative analysis of multi-omics reveals regulatory layers for diurnal gene expression in mouse liver

Diurnal oscillation persists throughout the body and plays an essential role in maintaining physiological homeostasis. Disruption of diurnal rhythm contributes to many diseases including type 2 diabetes. The regulatory mechanism of the transcription-translation feedback loop (TTFL) of core clock gen...

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Bibliographic Details
Main Authors: Chunjie Jiang, Panpan Liu, Cam Mong La, Dongyin Guan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
diurnal rhythm
multi-omics analysis
liver
gene expression
regulatory layer
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.955070/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.955070/full

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