Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report

Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after adm...

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Main Authors: Serge Goldman, Dominique Bron, Thomas Tousseyn, Irina Vierasu, Laurent Dewispelaere, Pierre Heimann, Elie Cogan, Michel Goldman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.798095/full
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author Serge Goldman
Dominique Bron
Thomas Tousseyn
Irina Vierasu
Laurent Dewispelaere
Pierre Heimann
Elie Cogan
Michel Goldman
author_facet Serge Goldman
Dominique Bron
Thomas Tousseyn
Irina Vierasu
Laurent Dewispelaere
Pierre Heimann
Elie Cogan
Michel Goldman
author_sort Serge Goldman
collection DOAJ
description Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.
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spelling doaj.art-203b9a84312a421abc0475ff22e445182022-12-21T20:34:04ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-11-01810.3389/fmed.2021.798095798095Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case ReportSerge Goldman0Dominique Bron1Thomas Tousseyn2Irina Vierasu3Laurent Dewispelaere4Pierre Heimann5Elie Cogan6Michel Goldman7Department of Nuclear Medicine, Erasme Hospital, Université Libre de Bruxelles, Brussels, BelgiumDepartment of Hematology, Jules Bordet Institute, Université Libre de Bruxelles, Brussels, BelgiumDepartment of Pathology, UZ Leuven Hospitals, Leuven, BelgiumDepartment of Nuclear Medicine, Erasme Hospital, Université Libre de Bruxelles, Brussels, BelgiumLaboratory of Hematology, LHUB, Université Libre de Bruxelles, Brussels, BelgiumLaboratory of Hematology, LHUB, Université Libre de Bruxelles, Brussels, BelgiumDepartment of Internal Medicine, CHIREC Hospital, Brussels, BelgiumI3h Institute, Université Libre de Bruxelles, Brussels, BelgiumSince nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.https://www.frontiersin.org/articles/10.3389/fmed.2021.798095/fullmRNA vaccineT celllymphomaCOVID-19angioimmunoblasticfollicular
spellingShingle Serge Goldman
Dominique Bron
Thomas Tousseyn
Irina Vierasu
Laurent Dewispelaere
Pierre Heimann
Elie Cogan
Michel Goldman
Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
Frontiers in Medicine
mRNA vaccine
T cell
lymphoma
COVID-19
angioimmunoblastic
follicular
title Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
title_full Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
title_fullStr Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
title_full_unstemmed Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
title_short Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
title_sort rapid progression of angioimmunoblastic t cell lymphoma following bnt162b2 mrna vaccine booster shot a case report
topic mRNA vaccine
T cell
lymphoma
COVID-19
angioimmunoblastic
follicular
url https://www.frontiersin.org/articles/10.3389/fmed.2021.798095/full
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