Effect of Centella asiatica (L.) Urb. extracts through expression of SIRT1 and Per2 on zebrafish (Danio rerio) larvae insomnia model

Effect of Centella asiatica (L.) Urb. extracts through expression of SIRT1 and Per2 on zebrafish (Danio rerio) larvae insomnia model

Context: Insomnia is difficulty falling asleep or maintaining sleep or sleeping conditions that cannot adequately restore the body and mental state. However, insomnia therapy has not been satisfying for improving the condition. Several alternative therapy options for treating insomnia include Centel...

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Bibliographic Details
Main Authors: Zamroni Afif, Nurvia Andriani, Rodhiyan Rakhmatiar, Shahdevi Kurniawan, Holipah, Husnul Khotimah, Nurdiana, Irawan Satriotomo
Format: Article
Language:English
Published: GarVal Editorial Ltda. 2024-03-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
centella asiatica
circadian rhythm
deacetylase sirtuin-1
insomnia
period circadian regulator-2
zebrafish
Online Access:https://jppres.com/jppres/pdf/vol12/jppres23.1737_12.2.286.pdf

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