Chronic Intermittent Hypoxia-Induced Diaphragm Muscle Weakness Is NADPH Oxidase-2 Dependent

Chronic Intermittent Hypoxia-Induced Diaphragm Muscle Weakness Is NADPH Oxidase-2 Dependent

Chronic intermittent hypoxia (CIH)-induced redox alterations underlie diaphragm muscle dysfunction. We sought to establish if NADPH oxidase 2 (NOX2)-derived reactive oxygen species (ROS) underpin CIH-induced changes in diaphragm muscle, which manifest as impaired muscle performance. Adult male mice...

Full description

Bibliographic Details
Main Authors: Sarah E. Drummond, David P. Burns, Sarah El Maghrani, Oscar Ziegler, Vincent Healy, Ken D. O’Halloran
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
obstructive sleep apnoea
diaphragm
chronic intermittent hypoxia
NADPH oxidase
Online Access:https://www.mdpi.com/2073-4409/12/14/1834

Similar Items

Similar Items