Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS.
Since broflanilide is a newly developed pesticide, analytical methods are required to determine the corresponding pesticide residues in diverse crops and foods. In this study, a pesticide residue analysis method was optimized for the detection and quantification of broflanilide and its two metabolit...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0235526 |
| _version_ | 1819199576414879744 |
|---|---|
| author | Hyun Ho Noh Chang Jo Kim Hyeyoung Kwon Danbi Kim Byeong-Chul Moon Sujin Baek Min-Seok Oh Kee Sung Kyung |
| author_facet | Hyun Ho Noh Chang Jo Kim Hyeyoung Kwon Danbi Kim Byeong-Chul Moon Sujin Baek Min-Seok Oh Kee Sung Kyung |
| author_sort | Hyun Ho Noh |
| collection | DOAJ |
| description | Since broflanilide is a newly developed pesticide, analytical methods are required to determine the corresponding pesticide residues in diverse crops and foods. In this study, a pesticide residue analysis method was optimized for the detection and quantification of broflanilide and its two metabolites, DM-8007 and S(PFH-OH)-8007, in brown rice, soybean, apple, green pepper, mandarin, and kimchi cabbage. Residue samples were extracted from the produce using QuEChERS acetate and citrate buffering methods and were purified by dispersive solid-phase extraction (d-SPE) using six different adsorbent compositions with varying amounts of primary secondary amine (PSA), C18, and graphitized carbon black. All the sample preparation methods gave low-to-medium matrix effects, as confirmed by liquid chromatography-tandem mass spectrometry using standard solutions and matrix-matched standards. In particular, the use of the citrate buffering method, in combination with purification by d-SPE using 25 mg of PSA and a mixture of other adsorbents, consistently gave low matrix effects that in the range from -18.3 to 18.8%. Pesticide recoveries within the valid recovery range 70-120% were obtained both with and without d-SPE purification using 25 mg of PSA and other adsorbents. Thus, the developed residue analysis method is viable for the determination of broflanilide and its metabolites in various crops. |
| first_indexed | 2024-12-23T03:18:32Z |
| format | Article |
| id | doaj.art-2048aa89aa1f4736b2b64e9b28b5ce2b |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-23T03:18:32Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-2048aa89aa1f4736b2b64e9b28b5ce2b2022-12-21T18:02:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011510e023552610.1371/journal.pone.0235526Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS.Hyun Ho NohChang Jo KimHyeyoung KwonDanbi KimByeong-Chul MoonSujin BaekMin-Seok OhKee Sung KyungSince broflanilide is a newly developed pesticide, analytical methods are required to determine the corresponding pesticide residues in diverse crops and foods. In this study, a pesticide residue analysis method was optimized for the detection and quantification of broflanilide and its two metabolites, DM-8007 and S(PFH-OH)-8007, in brown rice, soybean, apple, green pepper, mandarin, and kimchi cabbage. Residue samples were extracted from the produce using QuEChERS acetate and citrate buffering methods and were purified by dispersive solid-phase extraction (d-SPE) using six different adsorbent compositions with varying amounts of primary secondary amine (PSA), C18, and graphitized carbon black. All the sample preparation methods gave low-to-medium matrix effects, as confirmed by liquid chromatography-tandem mass spectrometry using standard solutions and matrix-matched standards. In particular, the use of the citrate buffering method, in combination with purification by d-SPE using 25 mg of PSA and a mixture of other adsorbents, consistently gave low matrix effects that in the range from -18.3 to 18.8%. Pesticide recoveries within the valid recovery range 70-120% were obtained both with and without d-SPE purification using 25 mg of PSA and other adsorbents. Thus, the developed residue analysis method is viable for the determination of broflanilide and its metabolites in various crops.https://doi.org/10.1371/journal.pone.0235526 |
| spellingShingle | Hyun Ho Noh Chang Jo Kim Hyeyoung Kwon Danbi Kim Byeong-Chul Moon Sujin Baek Min-Seok Oh Kee Sung Kyung Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS. PLoS ONE |
| title | Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS. |
| title_full | Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS. |
| title_fullStr | Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS. |
| title_full_unstemmed | Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS. |
| title_short | Optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the QuEChERS method and LC-MS/MS. |
| title_sort | optimized residue analysis method for broflanilide and its metabolites in agricultural produce using the quechers method and lc ms ms |
| url | https://doi.org/10.1371/journal.pone.0235526 |
| work_keys_str_mv | AT hyunhonoh optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT changjokim optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT hyeyoungkwon optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT danbikim optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT byeongchulmoon optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT sujinbaek optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT minseokoh optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms AT keesungkyung optimizedresidueanalysismethodforbroflanilideanditsmetabolitesinagriculturalproduceusingthequechersmethodandlcmsms |