СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN
In patients with arterial hypertension (HT) heart is affected earlier and more often than other target organs, left ventricular hypertrophy (LVH) develops. Considering the proven link between the presence of LVH and increased cardiovascular risk, the deterioration of the clinical course and prognosi...
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Format: | Article |
Language: | English |
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Столичная издательская компания
2015-09-01
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Series: | Рациональная фармакотерапия в кардиологии |
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Online Access: | http://www.rpcardio.ru/jour/article/view/277 |
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author | I. I. Chukaeva Ya. G. Spiryakina |
author_facet | I. I. Chukaeva Ya. G. Spiryakina |
author_sort | I. I. Chukaeva |
collection | DOAJ |
description | In patients with arterial hypertension (HT) heart is affected earlier and more often than other target organs, left ventricular hypertrophy (LVH) develops. Considering the proven link between the presence of LVH and increased cardiovascular risk, the deterioration of the clinical course and prognosis in HT patients, as well as a significant prognosis improvement in patients with LVH decrease, correction of modifiable risk factors (including uncontrolled HT) is getting extremely important. Organoprotective properties of drugs should be taken into account as one of the important parameters in the consideration of antihypertensive therapy. Major studies conducted in recent years have proven cardioprotective and angioprotective properties of angiotensin receptor blocker losartan, so it can be used as first-line therapy in patients with HT and LVH. |
first_indexed | 2024-03-12T04:31:32Z |
format | Article |
id | doaj.art-204d63d81722419ea5c9e8d538d4547e |
institution | Directory Open Access Journal |
issn | 1819-6446 2225-3653 |
language | English |
last_indexed | 2024-03-12T04:31:32Z |
publishDate | 2015-09-01 |
publisher | Столичная издательская компания |
record_format | Article |
series | Рациональная фармакотерапия в кардиологии |
spelling | doaj.art-204d63d81722419ea5c9e8d538d4547e2023-09-03T10:02:48ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019666066310.1234/1819-6446-2013-6-660-663277СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTANI. I. Chukaeva0Ya. G. Spiryakina1Российский национальный исследовательский медицинский университет имени Н.И. ПироговаРоссийский национальный исследовательский медицинский университет имени Н.И. ПироговаIn patients with arterial hypertension (HT) heart is affected earlier and more often than other target organs, left ventricular hypertrophy (LVH) develops. Considering the proven link between the presence of LVH and increased cardiovascular risk, the deterioration of the clinical course and prognosis in HT patients, as well as a significant prognosis improvement in patients with LVH decrease, correction of modifiable risk factors (including uncontrolled HT) is getting extremely important. Organoprotective properties of drugs should be taken into account as one of the important parameters in the consideration of antihypertensive therapy. Major studies conducted in recent years have proven cardioprotective and angioprotective properties of angiotensin receptor blocker losartan, so it can be used as first-line therapy in patients with HT and LVH.http://www.rpcardio.ru/jour/article/view/277артериальная гипертониягипертрофия левого желудочкаантигипертензивная терапиякардиопротекциялозартан |
spellingShingle | I. I. Chukaeva Ya. G. Spiryakina СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN Рациональная фармакотерапия в кардиологии артериальная гипертония гипертрофия левого желудочка антигипертензивная терапия кардиопротекция лозартан |
title | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_full | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_fullStr | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_full_unstemmed | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_short | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_sort | сardioprotection in patients with hypertension the role of losartan |
topic | артериальная гипертония гипертрофия левого желудочка антигипертензивная терапия кардиопротекция лозартан |
url | http://www.rpcardio.ru/jour/article/view/277 |
work_keys_str_mv | AT iichukaeva sardioprotectioninpatientswithhypertensiontheroleoflosartan AT yagspiryakina sardioprotectioninpatientswithhypertensiontheroleoflosartan |