Endoplasmic Reticulum Stress and Autophagy Are Involved in Hepatotoxicity Induced by Tributyltin

Endoplasmic Reticulum Stress and Autophagy Are Involved in Hepatotoxicity Induced by Tributyltin

Tributyltin (TBT), a common contaminant in aquatic ecosystems, has severe toxic effects on multiple tissues and organs, especially the liver. Previous toxicogenomic analysis has indicated that the main mechanism of TBT-induced hepatotoxicity is related to the activation of the apoptotic pathway. How...

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Bibliographic Details
Main Authors: Weiqi Liang, Lingling Fu, Mei Feng, Xiaorong Wang, Zhaohui Yun, Jin Xu
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Toxics
Subjects:
tributyltin
hepatotoxicity
proteomics
endoplasmic reticulum stress
autophagy
Online Access:https://www.mdpi.com/2305-6304/11/7/607

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