Myocardin‐related transcription factor's interaction with serum‐response factor is critical for outgrowth initiation, progression, and metastatic colonization of breast cancer cells

Myocardin‐related transcription factor's interaction with serum‐response factor is critical for outgrowth initiation, progression, and metastatic colonization of breast cancer cells

Abstract Breast cancer (BC)‐related mortality primarily results from metastatic colonization of disseminated cells. Actin polymerization plays an important role in driving post‐extravasation metastatic outgrowth of tumor cells. This study examines the role of myocardin‐related transcription factor (...

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Bibliographic Details
Main Authors: David Gau, Pooja Chawla, Ian Eder, Partha Roy
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:FASEB BioAdvances
Subjects:
breast cancer
CCG‐1423
metastasis
MRTF
outgrowth
SRF
Online Access:https://doi.org/10.1096/fba.2021-00113

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