Craniofacial Development Is Fine-Tuned by Sox2

The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals...

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Bibliographic Details
Main Authors: Nikolaos Panagiotis Mandalos, Aikaterini Dimou, Maria Angeliki Gavala, Efstathia Lambraki, Eumorphia Remboutsika
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/2/380
Description
Summary:The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.
ISSN:2073-4425