Craniofacial Development Is Fine-Tuned by Sox2
The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/14/2/380 |
| _version_ | 1797620788826734592 |
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| author | Nikolaos Panagiotis Mandalos Aikaterini Dimou Maria Angeliki Gavala Efstathia Lambraki Eumorphia Remboutsika |
| author_facet | Nikolaos Panagiotis Mandalos Aikaterini Dimou Maria Angeliki Gavala Efstathia Lambraki Eumorphia Remboutsika |
| author_sort | Nikolaos Panagiotis Mandalos |
| collection | DOAJ |
| description | The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes. |
| first_indexed | 2024-03-11T08:46:36Z |
| format | Article |
| id | doaj.art-20557a62356c44679b42356b2d420ebd |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-11T08:46:36Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-20557a62356c44679b42356b2d420ebd2023-11-16T20:42:11ZengMDPI AGGenes2073-44252023-01-0114238010.3390/genes14020380Craniofacial Development Is Fine-Tuned by Sox2Nikolaos Panagiotis Mandalos0Aikaterini Dimou1Maria Angeliki Gavala2Efstathia Lambraki3Eumorphia Remboutsika4University Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, GreeceUniversity Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, GreeceUniversity Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, GreeceUniversity Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, GreeceUniversity Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, GreeceThe precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.https://www.mdpi.com/2073-4425/14/2/380neural crest stem cellsneural stem cellsembryonic stem cellsinduced pluripotent stem cellsneural progenitor cellsneurogenesis |
| spellingShingle | Nikolaos Panagiotis Mandalos Aikaterini Dimou Maria Angeliki Gavala Efstathia Lambraki Eumorphia Remboutsika Craniofacial Development Is Fine-Tuned by Sox2 Genes neural crest stem cells neural stem cells embryonic stem cells induced pluripotent stem cells neural progenitor cells neurogenesis |
| title | Craniofacial Development Is Fine-Tuned by Sox2 |
| title_full | Craniofacial Development Is Fine-Tuned by Sox2 |
| title_fullStr | Craniofacial Development Is Fine-Tuned by Sox2 |
| title_full_unstemmed | Craniofacial Development Is Fine-Tuned by Sox2 |
| title_short | Craniofacial Development Is Fine-Tuned by Sox2 |
| title_sort | craniofacial development is fine tuned by sox2 |
| topic | neural crest stem cells neural stem cells embryonic stem cells induced pluripotent stem cells neural progenitor cells neurogenesis |
| url | https://www.mdpi.com/2073-4425/14/2/380 |
| work_keys_str_mv | AT nikolaospanagiotismandalos craniofacialdevelopmentisfinetunedbysox2 AT aikaterinidimou craniofacialdevelopmentisfinetunedbysox2 AT mariaangelikigavala craniofacialdevelopmentisfinetunedbysox2 AT efstathialambraki craniofacialdevelopmentisfinetunedbysox2 AT eumorphiaremboutsika craniofacialdevelopmentisfinetunedbysox2 |