Granulosa cell tumor in a six-year-old girl presented as precocious puberty

Ovarian sex cord-stromal tumors, including granulose cell tumors (GCTs), are a group of neoplasms that occur rarely, especially in children. Only 0.1 percent of all ovarian tumors and 4-5 percent of GCTs occur in children. The most common presentation of these tumors in children is precocious pubert...

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Main Authors: Mahin Hashemipour, Mohammad Hassan Moaddab, Masoud Nazem, Parvin Mahzouni, Mehdi Salek
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2010;volume=15;issue=4;spage=240;epage=242;aulast=Hashemipour
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author Mahin Hashemipour
Mohammad Hassan Moaddab
Masoud Nazem
Parvin Mahzouni
Mehdi Salek
author_facet Mahin Hashemipour
Mohammad Hassan Moaddab
Masoud Nazem
Parvin Mahzouni
Mehdi Salek
author_sort Mahin Hashemipour
collection DOAJ
description Ovarian sex cord-stromal tumors, including granulose cell tumors (GCTs), are a group of neoplasms that occur rarely, especially in children. Only 0.1 percent of all ovarian tumors and 4-5 percent of GCTs occur in children. The most common presentation of these tumors in children is precocious puberty. We report a 6 years old girl with isosexual precocity, presented as premature thelarche and vaginal bleeding. Ultrasonography of pelvis showed a hypoechoic solid mass of left ovary. Microscopic features of the resected mass were characteristic of juvenile GCT. Although in most of girls with precocious puberty, the etiology is idiopathic, important causes, such as ovarian tumors must be considered.
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spelling doaj.art-205a97a33d4b43f2962bf4bb98c401332022-12-22T00:13:54ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362010-01-01154240242Granulosa cell tumor in a six-year-old girl presented as precocious pubertyMahin HashemipourMohammad Hassan MoaddabMasoud NazemParvin MahzouniMehdi SalekOvarian sex cord-stromal tumors, including granulose cell tumors (GCTs), are a group of neoplasms that occur rarely, especially in children. Only 0.1 percent of all ovarian tumors and 4-5 percent of GCTs occur in children. The most common presentation of these tumors in children is precocious puberty. We report a 6 years old girl with isosexual precocity, presented as premature thelarche and vaginal bleeding. Ultrasonography of pelvis showed a hypoechoic solid mass of left ovary. Microscopic features of the resected mass were characteristic of juvenile GCT. Although in most of girls with precocious puberty, the etiology is idiopathic, important causes, such as ovarian tumors must be considered.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2010;volume=15;issue=4;spage=240;epage=242;aulast=HashemipourGranulosa Cell TumorPubertyChildren
spellingShingle Mahin Hashemipour
Mohammad Hassan Moaddab
Masoud Nazem
Parvin Mahzouni
Mehdi Salek
Granulosa cell tumor in a six-year-old girl presented as precocious puberty
Journal of Research in Medical Sciences
Granulosa Cell Tumor
Puberty
Children
title Granulosa cell tumor in a six-year-old girl presented as precocious puberty
title_full Granulosa cell tumor in a six-year-old girl presented as precocious puberty
title_fullStr Granulosa cell tumor in a six-year-old girl presented as precocious puberty
title_full_unstemmed Granulosa cell tumor in a six-year-old girl presented as precocious puberty
title_short Granulosa cell tumor in a six-year-old girl presented as precocious puberty
title_sort granulosa cell tumor in a six year old girl presented as precocious puberty
topic Granulosa Cell Tumor
Puberty
Children
url http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2010;volume=15;issue=4;spage=240;epage=242;aulast=Hashemipour
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AT mohammadhassanmoaddab granulosacelltumorinasixyearoldgirlpresentedasprecociouspuberty
AT masoudnazem granulosacelltumorinasixyearoldgirlpresentedasprecociouspuberty
AT parvinmahzouni granulosacelltumorinasixyearoldgirlpresentedasprecociouspuberty
AT mehdisalek granulosacelltumorinasixyearoldgirlpresentedasprecociouspuberty