Giant apocrine carcinoma of the breast: A case report with review

Invasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor...

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Bibliographic Details
Main Authors: Rajeshwari K. Muthusamy, Sangita S. Mehta
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2018-01-01
Series:Asian Journal of Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16
Description
Summary:Invasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor. We report a case of giant invasive apocrine carcinoma of the breast involving the entire breast parenchyma without skin and chest wall infiltration. The clinical, pathological, immunohistochemical, and ultrastructural findings are discussed with emphasis on morphological and immunohistochemical features that aid in the diagnosis of this rare tumor.
ISSN:2454-6798
2455-4618