Giant apocrine carcinoma of the breast: A case report with review
Invasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor...
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Format: | Article |
Language: | English |
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Thieme Medical Publishers, Inc.
2018-01-01
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Series: | Asian Journal of Oncology |
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Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16 |
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author | Rajeshwari K. Muthusamy Sangita S. Mehta |
author_facet | Rajeshwari K. Muthusamy Sangita S. Mehta |
author_sort | Rajeshwari K. Muthusamy |
collection | DOAJ |
description | Invasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor. We report a case of giant invasive apocrine carcinoma of the breast involving the entire breast parenchyma without skin and chest wall infiltration. The clinical, pathological, immunohistochemical, and ultrastructural findings are discussed with emphasis on morphological and immunohistochemical features that aid in the diagnosis of this rare tumor. |
first_indexed | 2024-12-11T04:16:04Z |
format | Article |
id | doaj.art-205da5a8ac0f40859d00497ccac2e3fc |
institution | Directory Open Access Journal |
issn | 2454-6798 2455-4618 |
language | English |
last_indexed | 2024-12-11T04:16:04Z |
publishDate | 2018-01-01 |
publisher | Thieme Medical Publishers, Inc. |
record_format | Article |
series | Asian Journal of Oncology |
spelling | doaj.art-205da5a8ac0f40859d00497ccac2e3fc2022-12-22T01:21:15ZengThieme Medical Publishers, Inc.Asian Journal of Oncology2454-67982455-46182018-01-01040102102410.4103/ASJO.ASJO_112_16Giant apocrine carcinoma of the breast: A case report with reviewRajeshwari K. Muthusamy0Sangita S. Mehta1Department of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, IndiaDepartment of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, IndiaInvasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor. We report a case of giant invasive apocrine carcinoma of the breast involving the entire breast parenchyma without skin and chest wall infiltration. The clinical, pathological, immunohistochemical, and ultrastructural findings are discussed with emphasis on morphological and immunohistochemical features that aid in the diagnosis of this rare tumor.http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16androgen receptorapocrine carcinomabreastelectron microscopyoncocytic carcinoma |
spellingShingle | Rajeshwari K. Muthusamy Sangita S. Mehta Giant apocrine carcinoma of the breast: A case report with review Asian Journal of Oncology androgen receptor apocrine carcinoma breast electron microscopy oncocytic carcinoma |
title | Giant apocrine carcinoma of the breast: A case report with review |
title_full | Giant apocrine carcinoma of the breast: A case report with review |
title_fullStr | Giant apocrine carcinoma of the breast: A case report with review |
title_full_unstemmed | Giant apocrine carcinoma of the breast: A case report with review |
title_short | Giant apocrine carcinoma of the breast: A case report with review |
title_sort | giant apocrine carcinoma of the breast a case report with review |
topic | androgen receptor apocrine carcinoma breast electron microscopy oncocytic carcinoma |
url | http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16 |
work_keys_str_mv | AT rajeshwarikmuthusamy giantapocrinecarcinomaofthebreastacasereportwithreview AT sangitasmehta giantapocrinecarcinomaofthebreastacasereportwithreview |