Giant apocrine carcinoma of the breast: A case report with review

Invasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor...

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Main Authors: Rajeshwari K. Muthusamy, Sangita S. Mehta
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2018-01-01
Series:Asian Journal of Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16
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author Rajeshwari K. Muthusamy
Sangita S. Mehta
author_facet Rajeshwari K. Muthusamy
Sangita S. Mehta
author_sort Rajeshwari K. Muthusamy
collection DOAJ
description Invasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor. We report a case of giant invasive apocrine carcinoma of the breast involving the entire breast parenchyma without skin and chest wall infiltration. The clinical, pathological, immunohistochemical, and ultrastructural findings are discussed with emphasis on morphological and immunohistochemical features that aid in the diagnosis of this rare tumor.
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spelling doaj.art-205da5a8ac0f40859d00497ccac2e3fc2022-12-22T01:21:15ZengThieme Medical Publishers, Inc.Asian Journal of Oncology2454-67982455-46182018-01-01040102102410.4103/ASJO.ASJO_112_16Giant apocrine carcinoma of the breast: A case report with reviewRajeshwari K. Muthusamy0Sangita S. Mehta1Department of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, IndiaDepartment of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, IndiaInvasive apocrine carcinoma of the breast is rare. The criteria for the diagnosis are uncertain with the variable reported incidence in the literature. The use of androgen receptor studies by immunohistochemistry and its potential response to androgen analogs necessitates the subtyping of this tumor. We report a case of giant invasive apocrine carcinoma of the breast involving the entire breast parenchyma without skin and chest wall infiltration. The clinical, pathological, immunohistochemical, and ultrastructural findings are discussed with emphasis on morphological and immunohistochemical features that aid in the diagnosis of this rare tumor.http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16androgen receptorapocrine carcinomabreastelectron microscopyoncocytic carcinoma
spellingShingle Rajeshwari K. Muthusamy
Sangita S. Mehta
Giant apocrine carcinoma of the breast: A case report with review
Asian Journal of Oncology
androgen receptor
apocrine carcinoma
breast
electron microscopy
oncocytic carcinoma
title Giant apocrine carcinoma of the breast: A case report with review
title_full Giant apocrine carcinoma of the breast: A case report with review
title_fullStr Giant apocrine carcinoma of the breast: A case report with review
title_full_unstemmed Giant apocrine carcinoma of the breast: A case report with review
title_short Giant apocrine carcinoma of the breast: A case report with review
title_sort giant apocrine carcinoma of the breast a case report with review
topic androgen receptor
apocrine carcinoma
breast
electron microscopy
oncocytic carcinoma
url http://www.thieme-connect.de/DOI/DOI?10.4103/ASJO.ASJO_112_16
work_keys_str_mv AT rajeshwarikmuthusamy giantapocrinecarcinomaofthebreastacasereportwithreview
AT sangitasmehta giantapocrinecarcinomaofthebreastacasereportwithreview