Clinical and genomic characterization of chemoradiation-resistant HPV-positive oropharyngeal squamous cell carcinoma

Clinical and genomic characterization of chemoradiation-resistant HPV-positive oropharyngeal squamous cell carcinoma

IntroductionMost patients with HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) have an excellent response to chemoradiation, and trials are now investigating de-escalated treatment. However, up to 25% of patients with HPV-positive OPSCC will experience recurrence, and up to 5% will even p...

Full description

Bibliographic Details
Main Authors: Theresa Guo, Fernando Zamuner, Stephanie Ting, Liam Chen, Lisa Rooper, Pablo Tamayo, Carole Fakhry, Daria Gaykalova, Ranee Mehra
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
HPV
oropharyngeal squamous cell carcinoma
platinum resistance
treatment resistance
persistent disease
genomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1336577/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1336577/full

Similar Items