Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy

The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful...

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Bibliographic Details
Main Author: E. V. Igolkina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2014-09-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/563
Description
Summary:The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful investigation and dispute. The paper gives the results of studies of the neurogenic component of pain in OA patients. There is sufficient evidence for the presence of sensory anomalies accompanying pain in OA. The clinical use of questionnaires to detect neuropathic pain may assist in identifying central sensitization in patients with OA. Medicaments for the symptomatic therapy of pain are characterized.
ISSN:1996-7012
2310-158X