Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy

The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful...

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Main Author: E. V. Igolkina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2014-09-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/563
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author E. V. Igolkina
author_facet E. V. Igolkina
author_sort E. V. Igolkina
collection DOAJ
description The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful investigation and dispute. The paper gives the results of studies of the neurogenic component of pain in OA patients. There is sufficient evidence for the presence of sensory anomalies accompanying pain in OA. The clinical use of questionnaires to detect neuropathic pain may assist in identifying central sensitization in patients with OA. Medicaments for the symptomatic therapy of pain are characterized.
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spelling doaj.art-2062903cc2554751bcf17d5b9f8f9e172023-03-13T08:39:23ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2014-09-0183667210.14412/1996-7012-2014-3-66-721864Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapyE. V. Igolkina0ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России, Москва, Россия 101000, Москва, ул. Трубецкая, д. 8, стр. 2The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful investigation and dispute. The paper gives the results of studies of the neurogenic component of pain in OA patients. There is sufficient evidence for the presence of sensory anomalies accompanying pain in OA. The clinical use of questionnaires to detect neuropathic pain may assist in identifying central sensitization in patients with OA. Medicaments for the symptomatic therapy of pain are characterized.https://mrj.ima-press.net/mrj/article/view/563больостеоартрозноцицепцияневропатическая больлечение боли
spellingShingle E. V. Igolkina
Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
Современная ревматология
боль
остеоартроз
ноцицепция
невропатическая боль
лечение боли
title Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_full Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_fullStr Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_full_unstemmed Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_short Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_sort current views of the development of pain syndrome mechanisms in patients with osteoarthrosis rational pharmacotherapy
topic боль
остеоартроз
ноцицепция
невропатическая боль
лечение боли
url https://mrj.ima-press.net/mrj/article/view/563
work_keys_str_mv AT evigolkina currentviewsofthedevelopmentofpainsyndromemechanismsinpatientswithosteoarthrosisrationalpharmacotherapy