Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain.

Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain.

<h4>Background</h4>Alterations in gene expression in the suicide brain have been reported and for several genes DNA methylation as an epigenetic regulator is thought to play a role. rRNA genes, that encode ribosomal RNA, are the backbone of the protein synthesis machinery and levels of r...

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Bibliographic Details
Main Authors: Patrick O McGowan, Aya Sasaki, Tony C T Huang, Alexander Unterberger, Matthew Suderman, Carl Ernst, Michael J Meaney, Gustavo Turecki, Moshe Szyf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18461137/pdf/?tool=EBI

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