Alpha-Ketoglutarate Promotes Goblet Cell Differentiation and Alters Urea Cycle Metabolites in DSS-Induced Colitis Mice

The metabolite, alpha-ketoglutarate (aKG), shows promise as an approach for ameliorating colitis, but much remains unknown about the full extent of its effects on the metabolome and mucosal barrier. To further elucidate this matter, C57BL/6 male mice received drinking water with or without 1% aKG fo...

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Bibliographic Details
Main Authors: Alejandro Bravo Iniguez, Qiyu Tian, Min Du, Mei-Jun Zhu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/6/1148

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