Cancer-on-chip: a 3D model for the study of the tumor microenvironment

Cancer-on-chip: a 3D model for the study of the tumor microenvironment

Abstract The approval of anticancer therapeutic strategies is still slowed down by the lack of models able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro models fail to recapitulate the organ and tissue structures, the fluid flows, and the mechanical stimul...

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Bibliographic Details
Main Authors: Elisa Cauli, Michela Anna Polidoro, Simona Marzorati, Claudio Bernardi, Marco Rasponi, Ana Lleo
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Biological Engineering
Subjects:
Cancer-on-chip
Tumor microenvironment
Metastasis
Organ-on-chip
Microfluidics
Pre-clinical models
Online Access:https://doi.org/10.1186/s13036-023-00372-6

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