Antibacterial activity of Ocimum gratissimum L. essential oil
The essential oil (EO) of Ocimum gratissimum inhibited Staphylococcus aureus at a concentration of 0.75 mg/ml. The minimal inhibitory concentrations (MICs) for Shigella flexineri, Salmonella enteritidis, Escherichia coli, Klebsiella sp., and Proteus mirabilis were at concentrations ranging from 3 to...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
1999-09-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000500022 |
| _version_ | 1827840501202550784 |
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| author | Celso Vataru Nakamura Tania Ueda-Nakamura Erika Bando Abrahão Fernandes Negrão Melo Díogenes Aparício Garcia Cortez Benedito Prado Dias Filho |
| author_facet | Celso Vataru Nakamura Tania Ueda-Nakamura Erika Bando Abrahão Fernandes Negrão Melo Díogenes Aparício Garcia Cortez Benedito Prado Dias Filho |
| author_sort | Celso Vataru Nakamura |
| collection | DOAJ |
| description | The essential oil (EO) of Ocimum gratissimum inhibited Staphylococcus aureus at a concentration of 0.75 mg/ml. The minimal inhibitory concentrations (MICs) for Shigella flexineri, Salmonella enteritidis, Escherichia coli, Klebsiella sp., and Proteus mirabilis were at concentrations ranging from 3 to 12 <FONT FACE="Symbol">m</FONT>g/ml. The endpoint was not reached for Pseudomonas aeruginosa (>=24 mg/ml). The MICs of the reference drugs used in this study were similar to those presented in other reports. The minimum bactericidal concentration of EO was within a twofold dilution of the MIC for this organism. The compound that showed antibacterial activity in the EO of O. gratissimum was identified as eugenol and structural findings were further supported by gas chromatography/mass spectra retention time data. The structure was supported by spectroscopic methods. |
| first_indexed | 2024-03-12T07:33:51Z |
| format | Article |
| id | doaj.art-2066aeff9b614186ae8843fb146b96c3 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T07:33:51Z |
| publishDate | 1999-09-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-2066aeff9b614186ae8843fb146b96c32023-09-02T21:33:28ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601999-09-0194567567810.1590/S0074-02761999000500022Antibacterial activity of Ocimum gratissimum L. essential oilCelso Vataru NakamuraTania Ueda-NakamuraErika BandoAbrahão Fernandes Negrão MeloDíogenes Aparício Garcia CortezBenedito Prado Dias FilhoThe essential oil (EO) of Ocimum gratissimum inhibited Staphylococcus aureus at a concentration of 0.75 mg/ml. The minimal inhibitory concentrations (MICs) for Shigella flexineri, Salmonella enteritidis, Escherichia coli, Klebsiella sp., and Proteus mirabilis were at concentrations ranging from 3 to 12 <FONT FACE="Symbol">m</FONT>g/ml. The endpoint was not reached for Pseudomonas aeruginosa (>=24 mg/ml). The MICs of the reference drugs used in this study were similar to those presented in other reports. The minimum bactericidal concentration of EO was within a twofold dilution of the MIC for this organism. The compound that showed antibacterial activity in the EO of O. gratissimum was identified as eugenol and structural findings were further supported by gas chromatography/mass spectra retention time data. The structure was supported by spectroscopic methods.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000500022Ocimum gratissimumessential oileugenolantimicrobial activity |
| spellingShingle | Celso Vataru Nakamura Tania Ueda-Nakamura Erika Bando Abrahão Fernandes Negrão Melo Díogenes Aparício Garcia Cortez Benedito Prado Dias Filho Antibacterial activity of Ocimum gratissimum L. essential oil Memorias do Instituto Oswaldo Cruz Ocimum gratissimum essential oil eugenol antimicrobial activity |
| title | Antibacterial activity of Ocimum gratissimum L. essential oil |
| title_full | Antibacterial activity of Ocimum gratissimum L. essential oil |
| title_fullStr | Antibacterial activity of Ocimum gratissimum L. essential oil |
| title_full_unstemmed | Antibacterial activity of Ocimum gratissimum L. essential oil |
| title_short | Antibacterial activity of Ocimum gratissimum L. essential oil |
| title_sort | antibacterial activity of ocimum gratissimum l essential oil |
| topic | Ocimum gratissimum essential oil eugenol antimicrobial activity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000500022 |
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