Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma
Abstract Papillary thyroid carcinoma is the most common type of thyroid cancer and accounts for almost 89.4% of all thyroid carcinomas. Hodgkin lymphoma is a heterogeneous group of neoplasms and represents 10% of lymphomas. These two cancers do not share the same risk factors. Some studies have repo...
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| Format: | Article |
| Language: | English |
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Wiley
2022-08-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.6246 |
| _version_ | 1811183141024432128 |
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| author | Maissa Ben Thayer Fatma Khanchel Imen Helal Dorra Chiboub Khouloud Ben Lazreg Raweh Hedhli Ehsen Ben Brahim Raja Jouini Aschraf Cheddli‐Debbich |
| author_facet | Maissa Ben Thayer Fatma Khanchel Imen Helal Dorra Chiboub Khouloud Ben Lazreg Raweh Hedhli Ehsen Ben Brahim Raja Jouini Aschraf Cheddli‐Debbich |
| author_sort | Maissa Ben Thayer |
| collection | DOAJ |
| description | Abstract Papillary thyroid carcinoma is the most common type of thyroid cancer and accounts for almost 89.4% of all thyroid carcinomas. Hodgkin lymphoma is a heterogeneous group of neoplasms and represents 10% of lymphomas. These two cancers do not share the same risk factors. Some studies have reported the association of thyroid papillary carcinoma with lymphomas, mainly Hodgkin's lymphoma, treated with radiotherapy. However, to our knowledge less than 10 cases have illustrated synchronous papillary thyroid carcinoma and Hodgkin lymphoma with no history of radiotherapy. We present the case of a 49‐year‐old female patient, with no history of past exposure to radiation, who was incidentally diagnosed with Hodgkin lymphoma during the work up for papillary thyroid carcinoma. Our patient had total thyroïdectomy with cervical lymphadenectomy. The histopathologic examination concluded to a papillary thyroid carcinoma of classical variant. And the lymph node dissection enabled us to diagnose not only papillary thyroid carcinoma's lymph node metastasis, but also Hodgkin Lymphoma. This discovery of the Hodgkin lymphoma was totally incidental. The discovery of synchronous tumors in patients with papillary thyroid carcinoma has been reported in the literature. However, the diagnosis of Hodgkin through lymph node dissection for papillary thyroid carcinoma is extremely rare. This underlines the singularity and the importance of our case. The synchronous papillary thyroid carcinoma and Hodgkin lymphoma is a rare condition, which may pose significant diagnostic and treatment dilemmas. To date, there is no standardized approach due to lack of experience. The molecular mechanisms of this link are poorly understood and yet remain to be elucidated. |
| first_indexed | 2024-04-11T09:41:46Z |
| format | Article |
| id | doaj.art-2068223a73f64260b9b11afa78f98372 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-11T09:41:46Z |
| publishDate | 2022-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-2068223a73f64260b9b11afa78f983722022-12-22T04:31:10ZengWileyClinical Case Reports2050-09042022-08-01108n/an/a10.1002/ccr3.6246Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinomaMaissa Ben Thayer0Fatma Khanchel1Imen Helal2Dorra Chiboub3Khouloud Ben Lazreg4Raweh Hedhli5Ehsen Ben Brahim6Raja Jouini7Aschraf Cheddli‐Debbich8Faculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaDepatment of Pathology Habib Thameur's Hospital Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaFaculty of Medicine of Tunis Tunis El Manar University Tunis TunisiaAbstract Papillary thyroid carcinoma is the most common type of thyroid cancer and accounts for almost 89.4% of all thyroid carcinomas. Hodgkin lymphoma is a heterogeneous group of neoplasms and represents 10% of lymphomas. These two cancers do not share the same risk factors. Some studies have reported the association of thyroid papillary carcinoma with lymphomas, mainly Hodgkin's lymphoma, treated with radiotherapy. However, to our knowledge less than 10 cases have illustrated synchronous papillary thyroid carcinoma and Hodgkin lymphoma with no history of radiotherapy. We present the case of a 49‐year‐old female patient, with no history of past exposure to radiation, who was incidentally diagnosed with Hodgkin lymphoma during the work up for papillary thyroid carcinoma. Our patient had total thyroïdectomy with cervical lymphadenectomy. The histopathologic examination concluded to a papillary thyroid carcinoma of classical variant. And the lymph node dissection enabled us to diagnose not only papillary thyroid carcinoma's lymph node metastasis, but also Hodgkin Lymphoma. This discovery of the Hodgkin lymphoma was totally incidental. The discovery of synchronous tumors in patients with papillary thyroid carcinoma has been reported in the literature. However, the diagnosis of Hodgkin through lymph node dissection for papillary thyroid carcinoma is extremely rare. This underlines the singularity and the importance of our case. The synchronous papillary thyroid carcinoma and Hodgkin lymphoma is a rare condition, which may pose significant diagnostic and treatment dilemmas. To date, there is no standardized approach due to lack of experience. The molecular mechanisms of this link are poorly understood and yet remain to be elucidated.https://doi.org/10.1002/ccr3.6246case reportHodgkin lymphomanodal metastasispapillary thyroid carcinomasecondary primary cancersynchronous |
| spellingShingle | Maissa Ben Thayer Fatma Khanchel Imen Helal Dorra Chiboub Khouloud Ben Lazreg Raweh Hedhli Ehsen Ben Brahim Raja Jouini Aschraf Cheddli‐Debbich Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma Clinical Case Reports case report Hodgkin lymphoma nodal metastasis papillary thyroid carcinoma secondary primary cancer synchronous |
| title | Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma |
| title_full | Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma |
| title_fullStr | Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma |
| title_full_unstemmed | Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma |
| title_short | Incidental discovery of a Hodgkin lymphoma synchronous to a papillary thyroid carcinoma |
| title_sort | incidental discovery of a hodgkin lymphoma synchronous to a papillary thyroid carcinoma |
| topic | case report Hodgkin lymphoma nodal metastasis papillary thyroid carcinoma secondary primary cancer synchronous |
| url | https://doi.org/10.1002/ccr3.6246 |
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