Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio

The effects of Copper Sulfate (CuSO4) on repaired the histopthological changes on liver of Cyprinus carpio exposed to nano zinc oxide (N-ZnO) was determined in this study.Fish weight 150±10 g divided in to four groups.Fish in first group kept in dechlorinated water while the fish in second group exp...

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Main Authors: S.K.I. AL-Taee, A.H.A. AL-Hamdani
Format: Article
Language:Arabic
Published: University of Mosul, College of Veterinary Medicine 2014-12-01
Series:Iraqi Journal of Veterinary Sciences
Subjects:
Online Access:https://vetmedmosul.com/article_116942_1df1329c7db93bf924ad99f03b793eec.pdf
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author S.K.I. AL-Taee
A.H.A. AL-Hamdani
author_facet S.K.I. AL-Taee
A.H.A. AL-Hamdani
author_sort S.K.I. AL-Taee
collection DOAJ
description The effects of Copper Sulfate (CuSO4) on repaired the histopthological changes on liver of Cyprinus carpio exposed to nano zinc oxide (N-ZnO) was determined in this study.Fish weight 150±10 g divided in to four groups.Fish in first group kept in dechlorinated water while the fish in second group exposed to copper sulfate CuSO4 for 1 hour and in third group the fish was exposed to sub lethal concentration of N-ZnO (30ppm) for 7 days while the fish in fourth group exposed to sub lethal concentration of N-ZnO (30ppm) with CuSO4 (0.3mgL) for 1hour and then exposed continuously to N-ZnO for 7days. The microscopic examination for the liver done through 24 hour and 7 days from the experiment, which revealed vacuolar degeneration in hepatic cells in fish exposed to N-ZnO for 24 hour also there were dilatation of sinusoid and infiltration of inflammatory cells in liver tissue of fish exposed to to N-ZnO with CuSO4 for 1 hour, there were slight hemorrhage in hepatic tissue and enlargement of hepatic cell in both groups exposed to N-ZnO and CuSO4 for 1 and 24 hour, while the microscopically examination of liver in fish exposed to N-ZnO for 7 days revealed sever pathological lesions characterized by hyperatrophy and necrosis in pancreatic tissue. This study concluded that N-ZnO can cause oxidative stress and usage of CuSO4 at 0.3 mg/L can decrease the toxic effects of N-ZnO liver tissue
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spelling doaj.art-206c3dcf50474352ad4a7b4a662bbb9a2022-12-22T03:16:23ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552014-12-012820010.33899/ijvs.2014.116942116942Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpioS.K.I. AL-TaeeA.H.A. AL-HamdaniThe effects of Copper Sulfate (CuSO4) on repaired the histopthological changes on liver of Cyprinus carpio exposed to nano zinc oxide (N-ZnO) was determined in this study.Fish weight 150±10 g divided in to four groups.Fish in first group kept in dechlorinated water while the fish in second group exposed to copper sulfate CuSO4 for 1 hour and in third group the fish was exposed to sub lethal concentration of N-ZnO (30ppm) for 7 days while the fish in fourth group exposed to sub lethal concentration of N-ZnO (30ppm) with CuSO4 (0.3mgL) for 1hour and then exposed continuously to N-ZnO for 7days. The microscopic examination for the liver done through 24 hour and 7 days from the experiment, which revealed vacuolar degeneration in hepatic cells in fish exposed to N-ZnO for 24 hour also there were dilatation of sinusoid and infiltration of inflammatory cells in liver tissue of fish exposed to to N-ZnO with CuSO4 for 1 hour, there were slight hemorrhage in hepatic tissue and enlargement of hepatic cell in both groups exposed to N-ZnO and CuSO4 for 1 and 24 hour, while the microscopically examination of liver in fish exposed to N-ZnO for 7 days revealed sever pathological lesions characterized by hyperatrophy and necrosis in pancreatic tissue. This study concluded that N-ZnO can cause oxidative stress and usage of CuSO4 at 0.3 mg/L can decrease the toxic effects of N-ZnO liver tissuehttps://vetmedmosul.com/article_116942_1df1329c7db93bf924ad99f03b793eec.pdfcopper sulfateliver damagenanozinc oxidecyprinus carpio
spellingShingle S.K.I. AL-Taee
A.H.A. AL-Hamdani
Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio
Iraqi Journal of Veterinary Sciences
copper sulfate
liver damage
nano
zinc oxide
cyprinus carpio
title Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio
title_full Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio
title_fullStr Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio
title_full_unstemmed Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio
title_short Effect of copper sulfate on liver damage induced by nano- zinc oxide in Cyprinus carpio
title_sort effect of copper sulfate on liver damage induced by nano zinc oxide in cyprinus carpio
topic copper sulfate
liver damage
nano
zinc oxide
cyprinus carpio
url https://vetmedmosul.com/article_116942_1df1329c7db93bf924ad99f03b793eec.pdf
work_keys_str_mv AT skialtaee effectofcoppersulfateonliverdamageinducedbynanozincoxideincyprinuscarpio
AT ahaalhamdani effectofcoppersulfateonliverdamageinducedbynanozincoxideincyprinuscarpio