Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives
Molecularly imprinted polymers (MIPs) are specific crosslinked polymers that exhibit binding sites for template molecules. MIPs have been developed in various application areas of biology and chemistry; however, MIPs have some problems, including an irregular material shape. In recent years, studies...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/14/3256 |
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| author | Tirza Ecclesia Orowitz Patria Pari Agnes Ago Ana Sombo Driyanti Rahayu Aliya Nur Hasanah |
| author_facet | Tirza Ecclesia Orowitz Patria Pari Agnes Ago Ana Sombo Driyanti Rahayu Aliya Nur Hasanah |
| author_sort | Tirza Ecclesia Orowitz |
| collection | DOAJ |
| description | Molecularly imprinted polymers (MIPs) are specific crosslinked polymers that exhibit binding sites for template molecules. MIPs have been developed in various application areas of biology and chemistry; however, MIPs have some problems, including an irregular material shape. In recent years, studies have been conducted to overcome this drawback, with the synthesis of uniform microsphere MIPs or molecularly imprinted microspheres (MIMs). The polymer microsphere is limited to a minimum size of 5 nm and a molecular weight of 10,000 Da. This review describes the methods used to produce MIMs, such as precipitation polymerisation, controlled/‘Living’ radical precipitation polymerisation (CRPP), Pickering emulsion polymerisation and suspension polymerisation. In addition, some green chemistry aspects and future perspectives will also be given. |
| first_indexed | 2024-03-10T18:25:24Z |
| format | Article |
| id | doaj.art-206d8a6c79ff4cefbc23947ce0252953 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T18:25:24Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-206d8a6c79ff4cefbc23947ce02529532023-11-20T07:02:22ZengMDPI AGMolecules1420-30492020-07-012514325610.3390/molecules25143256Microsphere Polymers in Molecular Imprinting: Current and Future PerspectivesTirza Ecclesia Orowitz0Patria Pari Agnes Ago Ana Sombo1Driyanti Rahayu2Aliya Nur Hasanah3Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM 21.5, Sumedang 45363, IndonesiaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM 21.5, Sumedang 45363, IndonesiaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM 21.5, Sumedang 45363, IndonesiaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM 21.5, Sumedang 45363, IndonesiaMolecularly imprinted polymers (MIPs) are specific crosslinked polymers that exhibit binding sites for template molecules. MIPs have been developed in various application areas of biology and chemistry; however, MIPs have some problems, including an irregular material shape. In recent years, studies have been conducted to overcome this drawback, with the synthesis of uniform microsphere MIPs or molecularly imprinted microspheres (MIMs). The polymer microsphere is limited to a minimum size of 5 nm and a molecular weight of 10,000 Da. This review describes the methods used to produce MIMs, such as precipitation polymerisation, controlled/‘Living’ radical precipitation polymerisation (CRPP), Pickering emulsion polymerisation and suspension polymerisation. In addition, some green chemistry aspects and future perspectives will also be given.https://www.mdpi.com/1420-3049/25/14/3256molecularly imprinted microspheremicrosphere polymerprecipitation polymerisationcontrolled/‘living’ radical precipitation polymerisationpickering emulsion polymerisationsuspension polymerisation |
| spellingShingle | Tirza Ecclesia Orowitz Patria Pari Agnes Ago Ana Sombo Driyanti Rahayu Aliya Nur Hasanah Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives Molecules molecularly imprinted microsphere microsphere polymer precipitation polymerisation controlled/‘living’ radical precipitation polymerisation pickering emulsion polymerisation suspension polymerisation |
| title | Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives |
| title_full | Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives |
| title_fullStr | Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives |
| title_full_unstemmed | Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives |
| title_short | Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives |
| title_sort | microsphere polymers in molecular imprinting current and future perspectives |
| topic | molecularly imprinted microsphere microsphere polymer precipitation polymerisation controlled/‘living’ radical precipitation polymerisation pickering emulsion polymerisation suspension polymerisation |
| url | https://www.mdpi.com/1420-3049/25/14/3256 |
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